Simultaneous measurement for brain disease by the combined system of Low field Magnetic resonance images and micro Magnetoencephalogram

本研究的目的是利用SQUID的被动和主动传感特性，建立脑磁图和磁共振成像的联合测量系统。我们现在正在开发一种低场MRI系统，它可以与小动物的MEG系统集成。该微型SQUID脑磁图系统可以检测到大鼠脑内癫痫棘波和诱发电位的飞秒特斯拉磁场。SQUID MRI在低场磁场中可以检测到水和脂质的T1信号，并能清晰地分离这两种信号。这一结果导致通过低场MRI构建2D成像。

This study aims to establish the simultaneous measurement of MEG and MRI combined system by the passive and active sensing of SQUID. We are now developing a low field MRI system which can be integrated with the MEG system for small animals. This micro SQUID MEG system could detect femtotesla magnetic fields of epileptic spike and evoked potential in rat brains. The SQUID MRI could detect the T1 signal of water and lipid in low field magnetic field, furthermore clearly separate these two signals. This result leads to construct 2D imaging by low field MRI.