Development of New Strategy for Analysis of Chromatographic Behavior on the Basis of Moment Theory

目前，为了提高高效液相色谱的分离速度和效率，人们开发了各种具有不同形状和孔隙度结构特征的分离介质，如硅胶单体、核壳球形颗粒等，使高效液相色谱成为精细分离和化学分析最有力的方法之一。本研究提出了一种新的方法（理论、实验方法和数据分析程序）来定量分析不同包装材料的分离性能和机理。该策略可以提供色谱行为的新信息，这是传统的理论和模型，如色谱的速率理论不能得到的。

Now, various separation media having different structural characteristics of shapes and porosities, such as silica monoliths and core-shell spherical particles, are developed for improving the separation speed and efficiency of high performance liquid chromatography, which has widely been used as one of the most powerful methods for fine separation and chemical analysis. In this study, a new strateg(theory, experimental method, and data analysis procedure) was developed for quantitatively analyzing the separation properties and mechanisms of the different packing materials in detail. The strategy can provide new information about chromatographic behavior, which cannot be derived by conventional theories and models, such as the rate theory of chromatography.