Reaction Mechanism of new vitamin E analog for protecting radiation injuries

对几种维生素E类似物进行了抗辐射所致小鼠骨髓死亡的研究，发现γ-生育酚二甲基甘氨酸酯是最有效的。它提高了小鼠在全身暴露于X射线或碳重原子辐射后的存活率。其作用机制可能与促进造血细胞的恢复有关。在小鼠异种移植模型上，该化合物不抑制局部碳重原子照射对肿瘤生长的抑制作用。

Several vitamin E analogs were examined against radiation-induced bone marrow death of mice and γ-tocopherol dimethylglycine ester was found to be most effective. It increased the survival of mice after whole body exposure of X-rays or carbon heavy atom radiation. The effect was found to be derived from the increase of the recovery of hematopoietic cells. The compound did not inhibit the control of tumor growth by local carbon heavy atom radiation using mouse xenograft model.