High density simulation for transcriptional dynamics

RNA聚合酶II（RNAPII）是负责转录的运动蛋白。在这里，我们研究了RNAPII基因转录动力学的细胞自动机模型的公式和结果，该模型考虑了根据基因位置（如内含子和外显子）发生的速度变化的影响。研究发现，只要最近的RNAPII分子之间的时间间隔大于RNAPII通过速度降低区域的排除长度所需的时间，尽管存在速度降低区域（如外显子），RNAPII分子仍以自由流动状态移动。

RNA polymerase II(RNAPII) is the responsible motor protein for transcription. Here we studied the formulation and results of a cellular automaton model of the RNAPII dynamics of gene transcription that takes account the effect of the velocity change according to the gene position, such as occurs in introns and exons. It was found that the RNAPII molecules move as a free-flow state, though regions of reduced velocity do exist such as exons, as far as the time interval between nearest RNAPII molecules is larger than the time required for an RNAPII passing the exclusion length in the velocity reduction region.