Search and clarification of a novel molecular function of 5-amonolevulinate

5-氨基乙酰丙酸（ALA）是几乎所有生物体都能自行产生的一种初级代谢产物。它的代谢产物四吡咯化合物，在血液和各种氧化酶中起重要作用，如血红素，N/S同化酶中的siroheme，植物中的叶绿素和维生素B12。此外，外部ALA喂养赋予植物对环境胁迫的抗性增加。在这项研究中，我们仔细研究了这些现象，并试图阐明分子机制。我们发现，外源ALA有助于恢复血红素，但不直接叶绿素和确定ALA诱导的转录因子从番茄和拟南芥。

5-aminolevulinic acid (ALA) is a primary metabolite which almost all living organism produce by theirselves. It's metabolic products, tetrapyrrole compounds, play critical roles as heme in blood and various oxidases, siroheme in N/S assimilation enzymes, chlorophyll in plant, and vitamin B12. Furthermore, external ALA-feeding confers increase of resistance to environmental stress to plants. In this study, we examined carefully the phenomena and tried to clarify the molecular mechanisms. We found that exogenous ALA contributes recovery of heme but not directly of chlorophyll and identified ALA-inducible transcription factors from tomato and Arabidopsis.