Fundamental studies for development of nursing interventions to improve autonomic neural functioning in the woman in late pregnancy

通过心率变异性(HRV)测量与生活质量相关的因素(睡眠、心理健康、疲劳)来评估妊娠晚期妇女的静息自主神经调节，发现睡眠对静息自主神经调节有显著影响。我们的下一项横断面研究对160名女性进行了调查，调查了睡眠障碍和HRV测量之间的关系，结果表明，习惯性打鼾者的静息自主神经调节向交感为主状态转变。我们对孕妇评估夜间血氧饱和度的进一步研究表明，在经历深度氧减饱和的妇女中，静息自主神经调节的副交感神经活性减弱。睡眠呼吸紊乱可能影响孕妇的静息自主神经调节，在干预措施改善孕妇自主神经功能之前，评估自主神经功能障碍的背景因素是很重要的。

The resting autonomic modulations in the women during late pregnancy were evaluated by heart rate variability (HRV) measures in relation to factors related to quality of life (sleep, mental health, fatigue), and significant impact was suggested in sleep. Our next cross-sectional study of 160 women investigating associations between sleep disturbances and HRV measures demonstrated that the resting autonomic modulations shifted toward a sympathetic predominant state in the women who are habitual snorers. Our further study of 64 pregnant women evaluating overnight oxygen saturation suggested that parasympathetic activity of the resting autonomic modulations is attenuated in women who underwent profound oxygen desaturation. The resting autonomic modulations in the pregnant women may be affected by sleep-disordered breathing, and it is important to evaluate the background factors of the autonomic dysfunctions prior to interventions to improve autonomic functioning in the pregnant women.