Evaluation for the prognostic index of SIRS and a target for blood purification therapy in dogs
Evaluation for the prognostic index of SIRS and a target for blood purification therapy in dogs
犬 SIRS 预后指标评价及血液净化治疗靶点
批准号：
24780310
负责人：
SHIMOKAWA Takako
金额：
$2.5万
依托单位国家：
日本
项目类别：
Grant-in-Aid for Young Scientists (B)
财政年份：
2012
资助国家：
日本
项目状态：
已结题
起止时间：
2012-04-01 至 2014-03-31
中文摘要
翻译
为探讨降钙素原作为全身炎症反应综合征(SIRS)预后指标和血液净化治疗靶点的可能性，建立了犬降钙素原酶联免疫吸附测定系统。通过克隆犬降钙素原基因，获得重组犬降钙素原蛋白和多克隆抗体。这些抗体能特异性识别犬降钙素原，并能通过酶联免疫吸附试验检测犬降钙素原。
英文摘要
To investigate the possibility of procalcitonin as a prognostic index of SIRS and a target for blood purification therapy in dogs, a measuring system for canine procalcitonin using ELISA has been established. A recombinant canine procalcitonin protein and polyclonal antibodies were obtained by cloning canine procalcitonin gene cDNA. These antibodies specifically recognized canine procalcitonin and was able to detect canine procalcitonin by ELISA.
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