Creation of hybrid-type carrier from lipid and peptide for functional nutraceuticals

酪蛋白和卵磷脂都是天然食品，也是必不可少的营养食品。此外，由于它们的性质，酪蛋白和脂质体被用来运送药物和营养食品。染料木素是已知的几种植物来源的异黄酮之一，在大豆中含量特别丰富。染料木素的抗氧化剂和植物雌激素特性与预防激素依赖型癌症有关。本研究以酪蛋白和脂质体为模型酪蛋白溶液作为染料木素的包封剂。据报道，牛奶蛋白消化产生的多肽具有抗氧化活性。金雀异黄素溶解在酪蛋白体系中，有望与酪蛋白在抗氧化能力上产生协同作用。虽然脂质体体系对染料木素的增溶没有协同作用，但磷脂脂质体能够包含大量的染料木素分子。这些可以相辅相成。

Both casein and lecithin are natural food products and also essential nutraceuticals. Furthermore, because of their properties, caseins and liposomes are used to deliver medicines and nutraceuticals. Genistein is one of several known plant-derived isoflavons; is particularly plentiful in soybeans. The antioxidant and phytoestrogen properties of genistein are associated with the prevention of hormone-dependent cancers. In this study, caseinate and liposomes were used as a model casein solution as a material for encapsulating genistein. Peptides generated from the digestion of milk proteins are reported to have antioxidative activities. Then it is expected that genistein will has synergisms effect in antioxidant capacity with caseinate, as it dissolved in the caseinate system. Although there is no synergisms effect in liposome system solubilizing genistein, the phospholipid liposome is able to include tremendously many genistein molecules. These can be complementary to each other.