Pediatric Neurointensive Care and Resuscitation Research

神经重症监护（NCC）是儿科重症监护医学（PCCM）的最后前沿。最常见的 儿科重症监护室（PICU）收治的婴儿和儿童的死亡原因是神经系统 导致认知障碍和生活质量降低的神经病的患病率 仍然高得不可接受。这个T32研究培训计划“儿科神经重症监护和 复苏研究，”成立于2000年，代表了一个独特的国家计划。它培养医学博士，博士， 基础，转化或临床研究的MD/PhD，来自治疗婴儿和儿童的七个部门 需要NCC的患者，从现场到急诊科、PICU， 康复和恢复。我们的具体目标是指导临床医生，特别是PCCM，儿童 神经病学，神经外科，PM&R，急诊医学，新生儿医学和放射学沿着 博士后博士科学家，在研究培训主要集中在两个侮辱，创伤性脑 损伤和心脏骤停。这两种情况是发达国家儿童NCC的主要贡献者。 世界我们的特色是萨法尔复苏研究中心和 匹兹堡大学医学中心匹兹堡儿童医院 建立一个高度协作、多学科和多部门的研究文化 训练我们的计划有一个精心策划的研究培训基础设施，已进一步完善 包括三个重点轨道（基础，转化和临床科学），每一个共享和独特的 件.它的特点是从24个国家认可的导师选择尖端项目，并提供 有机会获得高级学位或参加有针对性的课程，以加强职业发展。在这 优秀的环境培训生致力于实现五个目标：1）基于良好原则的教育， 当代神经科学，2）他们成为学术临床科学家或科学家，3）他们继续 获得独立的资金，4）他们最终成为该领域的领导者，5）他们完全 配备严格和道德的研究和成功开发新的神经保护，复苏， 再生疗法，并改善所有儿科NCC的神经结局。培训人员获得以下支持： 两三年那些在匹兹堡的教师职位的目标写K奖申请。然而，在这方面， 考虑到国家对儿科NCC研究中训练有素的研究人员的需求，我们的T32设计不仅仅是为了 培养本地人才。我们的学员不仅在匹兹堡发展成为独立资助的调查员， 但已成为该领域的国家领导者，在其他中心独立资助的研究人员， NIH资助的试验，NCC项目的主任，以及晋升和/或捐赠的教师。我们的成功也是 由我们的九个初级教师“未来导师”突出，谁是由R21或K奖资助，并担任 在我们的领域取得成功的杰出典范，以帮助指导我们的新学员。

Neurocritical care (NCC) is the final frontier in pediatric critical care medicine (PCCM). The most common cause of death in infants and children admitted to a pediatric intensive care unit (PICU) is neurological system failure and the prevalence of neuromorbidities causing cognitive impairment and reducing quality of life remains unacceptably high. This T32 research training program “Pediatric Neurointensive Care and Resuscitation Research,” established in 2000, represents a unique national program. It trains MDs, PhDs, and MD/PhDs in basic, translational, or clinical research, from seven departments that treat infants and children who require NCC across the continuum of care, from the field to the emergency department, the PICU, and to rehabilitation and recovery. Our Specific Aim is to mentor clinicians, specifically fellows in PCCM, Child Neurology, Neurosurgery, PM&R, Emergency Medicine, Newborn Medicine and Radiology along with postdoctoral PhD scientists, in research training focused predominantly around two insults, traumatic brain injury and cardiac arrest. Those two conditions are the leading contributors to pediatric NCC in the developed world. We feature the unique and formidable resources of the Safar Center for Resuscitation Research and the University of Pittsburgh Medical Center Children’s Hospital of Pittsburgh in the University of Pittsburgh School of Medicine to create a highly collaborative, multi-disciplinary and multi-departmental culture for research training. Our program has a carefully orchestrated research training infrastructure that has been further refined to include three focus tracks (basic, translational, and clinical science), each with shared and unique components. It features a choice of cutting-edge projects from 24 nationally recognized mentors, and offers opportunities to obtain advanced degrees or take targeted courses to enhance career development. In this outstanding environment trainees work to attain five goals 1) an education grounded in the sound principles of contemporary neuroscience, 2) that they become academic clinician-scientists or scientists, 3) that they go on to obtain independent funding, 4) that they ultimately become leaders in the field, and 5) that they are fully equipped to rigorously and ethically study and successfully develop novel neuroprotective, resuscitative, and regenerative therapies, and improve neuro-outcomes across all of pediatric NCC. Trainees are supported for two or three years. Those targeted for faculty positions in Pittsburgh write K award applications. However, given the National need for trained investigators in pediatric NCC research, our T32 is not designed simply to create local talent. Our trainees have not only developed into independently funded investigators in Pittsburgh, but have become National leaders in the field, independently funded investigators at other centers, site PIs for NIH-funded trials, directors of NCC programs, and promoted and/or Endowed faculty. Our success is also highlighted by our nine junior faculty “Future Mentors,” who are funded by R21 or K awards and serve as outstanding exemplars of success in our field, to help guide our new trainees.