Epilepsy Research Training Program

摘要 该提案旨在重新支持癫痫研究培训计划。的总体目标 计划是：（1）为学员提供广泛的基础，翻译和癫痫的临床理解 及其研究方法。(2)通过以下方式为学员提供执行高质量科学的工具 研讨会和讨论会涉及研究的定量方面，包括研究设计，统计， 和再现性。这些都是用解决问题的方法和实习生同侪小组授课. 讨论。(3)通过分配到不同的现代化培训机构，为学员提供最先进的科学培训。 实验室和严格执行个别委员会的监督。(4)为学员提供 科学相关的职业选择的各个方面的知识，并通过这些途径为他们做好准备 职业发展活动。(5)促进来自不同背景的受训人员的福祉和融合， 创建一个培训社区，在那里实习生在前和博士后水平交叉，交流榜样 和建议，并相互支持-从而提高个人和团体的成功。 癫痫研究培训计划将通过个性化，委员会， 在14位资金充足、热情洋溢的导师的实验室里进行监督研究培训。重要的是，培训 经验是丰富的程序特定的课程，讲习班，职业发展会议，受训者运行 会议，授权演讲，以及研讨会和专题讨论会，吸引了UCI神经科学 社区和潜在的学员。因此，癫痫研究培训计划为以下方面提供了附加值： 支持的学员以及众多参加我们活动并从中受益的学员。 我们迄今为止在实现雄心勃勃的培训目标方面取得的成功源于一批优秀的候选人， 以及与UCI癫痫研究中心和UCI临床癫痫计划的协同作用， 互动，提供多方面的培训体验。这些资产是由一个开放的， 互动的研究氛围，重要的资源，以及项目教师之间的丰富合作。 我们将癫痫作为“大脑可塑性窗口”的方法促进了基本方法和转化方法 研究癫痫及其认知和情感共病。 鉴于学术生涯的轨迹，我们的培训方法成功的切实措施是 随着癫痫研究培训项目进入第14个年头，这一点变得显而易见。 该项目是美国仅有的两个以癫痫为重点的T32项目之一，我们未来几年的目标是： 利用我们的成功，从学员和教师的投入中学习，以进一步提高培训体验： (1)从我们的5名博士前实习生，我们已经了解到博士后实习生互动的有益影响 （2）我们的目标是增加MD的招聘（目前为12%）， 来自不同背景的个人（目前占17%，占我们学员的六分之一）;）。(3)我们的目标是加强 教学的定量方面的研究，以及严格的研究，通过动手会议 与CTSA整合。因此，癫痫病培训计划将建立在其发射人才的记录之上。 神经科学家，包括少数民族和妇女进入可持续的学术生涯，从而提高未来 在神经科学研究的劳动力。

Abstract This proposal aims to renew support for a Training Program in Epilepsy Research. The overall goals of the Program are to: (1) Provide Trainees with a broad basic, translational and clinical understanding of Epilepsy and the approaches for its study. (2) Provide Trainees with the tools to perform top-quality science via workshops and discussions that address quantitative aspects of research, including study design, statistics, and reproducibility. These are taught in small groups using problem- solving approaches and Trainee peer- discussions. (3) Provide Trainees with state of the art scientific training via assignment to diverse modern laboratories and rigorous implementation of oversight by individualized committees. (4) Provide Trainees with the knowledge of the diverse facets of Science-related career choices and prepare them for these paths via career development activities. (5) Facilitate well-being and integration of Trainees from diverse backgrounds by creating a Training Community where trainees at pre-and postdoctoral level intersect, exchange role models and advice, and support one another- thus enhancing individual and group success. The Training Program in Epilepsy Research will accomplish these goals via individualized, committee- supervised research training in the labs of 14 well-funded and enthusiastic Mentors. Importantly, the training experience is enriched by program-specific courses, workshops, career-development sessions, Trainee-run gatherings, mandated presentations, as well as seminars and symposia that draw in the UCI Neuroscience community and potential trainees. The Training Program in Epilepsy Research thus provides added value to supported trainees as well as to numerous Trainees who join and benefit from our activities. Our success to date in achieving our ambitious training goals derives from an outstanding pool of candidates, and from synergy with the UCI Epilepsy Research Center and the UCI Clinical Epilepsy Program, which interact to provide a multifaceted Training Experience. These assets are complemented by an open and interactive research atmosphere, significant resources, and abundant collaborations among Program faculty. Our approach to Epilepsy as “a Window to Brain Plasticity” promotes both basic and translational approaches to research on Epilepsy and its cognitive and emotional co-morbidities. Given the trajectories of academic careers, tangible measures of success of our training approach are becoming evident as the Training Program in Epilepsy Research is in its 14th year. Our goal for the coming years of the Program, one of only two Epilepsy-focused T32s in the U.S, are to capitalize on our success and learn from trainee and faculty input to further enhance the training experience: (1) From our 5 pre-doctoral Trainees, we have learnt the beneficial effects of pre-postdoc trainee interactions to both, and request that maintain this structure; (2) We aim to increase MD recruitment (currently 12%), and that of individuals from diverse backgrounds (currently 17%, a sixth of our Trainees);). (3) We aim to intensify teaching of the quantitative aspects of research as well as of rigorous research via hands-on sessions integrated with the CTSA. Thus, the Training Program in Epilepsy will build on its record of launching talented Neuroscientists, including minority and women into sustainable academic careers, thus enhancing the future workforce in Neuroscience Research.