Supplement: Long-term Effects of the Family Check-up on Depression and Suicide Across Trials and Development

项目摘要 本申请作为紧急竞争性修订提交，以响应NOT-MH-20-047，“ 特别利益（NOSI）关于行政补充和紧急竞争的可用性 2019年新型冠状病毒心理健康研究的修订，”代表了我们的范围的变化， 目前资助的R 01，旨在研究FCU对抑郁症的长期交叉效应， 使用综合数据分析三项随机试验的自杀风险。这些随机试验包括 大样本的儿童和家庭谁收到FCU在幼儿和中学。当时， FCU是作为一个面对面的模式提供的，并经过调整，既适合学校，也适合家庭。由于 与此同时，FCU已被改编为在线版本，该版本对中学生有效， 增强养育子女的自我效能和减少儿童情绪问题（Stormshak等人，2019年）。鉴于 COVID-19大流行对父母和孩子的功能产生了广泛的负面影响，迫切需要 需要有效的以家庭为重点的预防/干预方案，可采用远程保健服务 在目前的流行病和未来类似规模的公共卫生危机中，以各种形式向家庭提供服务。 拟议的行政补充将调整和测试家庭在线检查的功效， 治疗，以培养适应新冠肺炎大流行的家庭功能。我们将测试 在一项随机临床试验中，对150个10 - 14岁青少年家庭进行了改编的FCU在线计划 年，并在6个月内的4个时间点进行评估。我们将研究适应FCU的效果 在线讨论变化的关键机制，包括育儿技巧、父母抑郁症和父母/子女自我- 监管，我们预测将直接影响儿童和家庭的功能。我们预测，这些关键的变化 干预的目标将影响参与者对COVID-19大流行的反应，包括青年 抑郁症和行为问题，科普流行性压力源的能力（例如， 就业状况或职能的变化;采取强制性安全措施），以及社会/家庭 功能（包括关系支持和家庭暴力风险）。

Project Summary This application, submitted as an Urgent Competitive Revision in response to NOT-MH-20-047, “Notice of Special Interest (NOSI) regarding the Availability of Administrative Supplements and Urgent Competitive Revisions for Mental Health Research on the 2019 Novel Coronavirus,” represents a change in scope from our currently-funded R01, which seeks to examine the long-term crossover effects of the FCU on depression and suicide-risk using Integrative Data Analysis across three randomized trials. These randomized trials include a large sample of children and families who received the FCU in early childhood and middle school. At that time, the FCU was delivered as an in-person model, and was adapted for both school and home delivery. Since that time, the FCU has been adapted to an online version which has been effective with middle school youth at enhancing parenting self-efficacy and reducing child emotional problems (Stormshak et al., 2019). Given the wide-ranging negative effects of the COVID-19 pandemic on parent and child functioning, there is an urgent need for effective family-focused prevention/intervention programming that can employ telehealth-delivery formats to reach families in the midst of the current pandemic and future public health crises of similar scale. The proposed administrative supplement will adapt and test the efficacy of the Family Check-Up Online as a treatment to foster resilient family functioning in response to the COVID-19 pandemic. We will test the effects of the adapted FCU Online program in a randomized clinical trial with 150 families with youth aged 10 – 14 years, and assessed over 4 time-points across 6 months. We will examine the effects of the adapted FCU Online on key mechanisms of change, including parenting skills, parental depression, and parent/child self- regulation, that we predict will directly impact child and family functioning. We predict that changes in these key targets of the intervention will impact participant’s response to the COVID-19 pandemic, including youth depression and behavior problems, the ability to cope with pandemic-focused stressors (e.g. dealing with changes in employment status or functioning; following mandated safety measures), and social/familial functioning (including relational support and risk for domestic violence).