Heat Indicators for Global Health: Surveillance, Early Warning Systems and adaptation-mitigation actions to reduce heat impacts in pregnant women, infants and health workers in the EU and Africa (HIGH Horizons)

欧盟和全球在监测气候变化和健康方面存在重大差距，因此很难追踪健康负担和政策结果。全球健康热指标(高地平线)：孕妇和产后妇女、婴幼儿和卫生工作者的监测、预警系统和卫生设施干预(高地平线)项目将在四年内进行，涉及一个英国合作伙伴、六个欧盟合作伙伴、三个非洲合作伙伴和一个国际组织(世卫组织)。它以受气候变化影响的弱势群体为中心：孕妇和产后妇女、婴儿和卫生工作者，这些群体受到气候变化的严重影响。我们将量化和监测极端高温对健康的直接和间接影响；测试个性化预警系统(EWS)；并在卫生设施中实施综合适应-缓解行动。使用瑞典、意大利拉齐奥、希腊以及肯尼亚和南非的卫生设施的数据进行的热影响分析和数据科学预测建模是所有活动的基础。在希腊的一个准母婴队列中，将在怀孕期间和婴儿中测量特定的生物标志物，以解释高温暴露对健康不利影响的作用。这些分析和系统审查为测试和选择全球、欧盟和国家指标提供了信息。分析还为EWS的截止阈值提供信息，按风险组分层。一款智能手机应用程序(气候应用程序-MCH)将提供警告和特定于设置的消息，由当地联合设计。这款应用程序将在瑞典、南非和津巴布韦的200名母亲和婴儿中进行评估，范围从产前到婴儿12个月。同时，我们将记录热暴露对卫生工作者的福祉、健康、生产力和护理质量的影响，包括通过时间运动研究。对卫生设施的修改将共同设计和建模，以减少卫生工作者的热暴露，并限制设施的碳排放。卫生工作者的结果和设施排放将在干预前后进行比较。权衡成本和收益的分析是所有活动的核心。在整个过程中，我们将向相关利益攸关方传播项目结果，优先考虑欧盟和全球政策制定者，并利用现有网络。关于气候变化和孕产妇、新生儿和儿童健康的最后一套指标将在世卫组织、联合国儿童基金会、世界气象组织和人口基金的指导文件中公布。为了优化协同作用，避免重叠，并增加从呼吁范围内选择供资的项目的影响-HLTH2021年-ENVHLTH-02-03(气候变化的健康影响，行动和不行动的成本和好处)，地平线欧洲项目(101057843高地平线、101057131催化、101057764蓝色适应、101057690气候、1057554IDAlert和101057739触发)将形成一个气候与健康组。共同的分组活动将包括分组年度会议和联合活动的定期报告；共同的传播和传播活动，包括分组的共同传播和通信战略、分组门户网站和视觉识别、分组小册子、分组通讯、利益攸关方名单、分组伙伴之间共享的个人数据管理计划、分组的政策战略，包括分组的联合政策简报和科学战略。关于共同感兴趣的问题的专题讲习班/培训应在专题组的科学战略范围内确定；关于共同感兴趣的主题的工作组

There are major gaps in surveillance of climate change and health in the EU and globally, making it difficult to track health burdens and policy outcomes. The Heat Indicators for Global Health (HIGH Horizons): monitoring, Early Warning Systems and health facility interventions for pregnant and postpartum women, infants and young children and health workers (HIGH Horizons) project, to be conducted over four years, involves one UK partner along with six partners in the EU, three in Africa and one international organisations (WHO). It centres on vulnerable groups affected by climate change: pregnant and postpartum women, infants, and health workers, groups heavily affected by climate change. We will quantify and monitor direct and indirect health impacts of extreme heat; test a personalised Early Warning System (EWS); and implement integrated adaptation-mitigation actions in health facilities. Analyses of heat impacts and data science predictive modelling using data from Sweden; Lazio Italy, Greece and health facilities in Kenya and South Africa underpin all activities. Specific biomarkers will be measured during pregnancy and in infants in a prospective mother-childbirth cohort in Greece to explain the role of heat exposures on adverse health effects. These analyses and systematic reviews inform testing and selection of global, EU and national indicators. Analyses also inform cut-off thresholds for EWSs, stratified by risk groups. A smartphone app (ClimApp-MCH) will deliver warnings and setting-specific messages, co-designed locally. The app will be evaluated among 200 mothers and infants in Sweden, South Africa and Zimbabwe, from antepartum through 12 months of infant age. Simultaneously, we will document impacts of heat exposure on health worker wellbeing, health, productivity and quality of care, including through time-motion studies. Modifications to health facilities will be co-designed and modelled to reduce heat exposure for health workers and to limit facilities carbon emissions. Health worker outcomes and facility emissions will be compared pre- and postintervention. Analyses weighing costs and benefits are central to all activities. Throughout we will disseminate project findings to relevant stakeholders, prioritising EU and global policy makers and leveraging existing networks. The final set of indicators on climate change and maternal, newborn and child health will be released in a WHO, UNICEF, WMO and UNFPA guidance document.In order to optimise synergies, avoid overlaps and increase the impact of the projects selected for funding from the call HORIZON-HLTH-2021-ENVHLTH-02-03 (Health impacts of climate change, costs and benefits of action and inaction), Horizon Europe projects 101057843 HIGH Horizons, 101057131 CATALYSE, 101057764 BlueAdapt, 101057690 CLIMOS, 101057554 IDAlert and 101057739 TRIGGER) will form a Climate and Health cluster. Common cluster activities will include Annual cluster meetings and periodic report of joint activities; Common dissemination and communication activities, including a common dissemination and communication strategy for the cluster, cluster web portal and visual identity, cluster brochure, cluster newsletters, stakeholder list, Shared individual Data Management Plans between cluster partners, Policy Strategy of the cluster, including joint policy briefs and Scientific strategy of the cluster. Thematic workshops/trainings on issues of common interest be defined in the context of the scientific strategy of the cluster; Working groups on topics of common interest