Strengthening regional stem cells based research for advancement of multi modal innovative strategy for modelling neurodevelopmental disorders

神经发育障碍（NDD）是由早期脑发育的改变引起的一组复杂和异质性障碍，其引起精神疾病，如自闭症谱系障碍、智力残疾、精神分裂症和双相情感障碍。NDD具有很高的社会经济影响，并且患有NDD和精神健康问题的患者在地理上分散。因此，需要建立具有同等研究能力和业务守则的高能力区域中心，以便开展全球研究活动。流线的目标是加强战略网络，加强分子遗传学和遗传工程研究所（IMGGE）的研究和创新潜力，以发展IMGGE作为西巴尔干地区NDD研究的高容量中心，能够与欧洲的类似中心相结合。这将通过IMGGE与欧洲三个顶级研究机构的结对来实现：卡迪夫大学，马斯特里赫特大学和研究与技术中心。该项目的目标是：（a）加强和扩大研究所与国际领先的欧洲合作伙伴和区域合作伙伴之间目前的总体战略网络活动;（B）提高研究人员的研究形象和研究所在国家荒漠化和退化方面的科学吸引力;（c）加强研究所工作人员的研究管理能力和行政技能;（d）成为解决国家荒漠化和退化方面创新的区域领导者。将通过联网、工作人员交流、培训、暑期学校、专题讨论会、讲习班、参加会议以及在科学界、工业界和公众中传播来实现目标。与合作伙伴结对将提供新的研究途径、创造力、新方法的开发和合格科学家的更大流动性（对内和对外）。

Neurodevelopmental disorders (NDDs) caused by alterations in early brain development are a group of complex and heterogeneous disorders that give rise to the psychiatric conditions such as autism spectrum disorders, intellectual disability, schizophrenia and bipolar disorder. NDDs have a high socio-economic impact and patients with NDDs and mental health problems are geographically dispersed. Thus, establishment of high capacity regional centres with equivalent research capacity and codes of practice is needed in order to build global research activity. The goals of STREAMLINE are to enhanced strategic networking and reinforce research and innovation potential of the Institute of Molecular Genetics and Genetic Engineering (IMGGE) in order to develop IMGGE as a high capacity hub for research of NDDs in the Western Balkans which is able to integrate with similar centres in Europe. This will be achieved by twinning IMGGE with three top-class research institutions in Europe: Cardiff University, University of Maastricht and Centre for Research and Technology. The project objectives are: a) to enhance the current and scale up the overall strategic networking activities between the IMGGE and internationally-leading European partners and regional partners; b) to raise the research profile of research stuff and scientific attractiveness of IMGGE in the field of NDDs; c) to strengthens research management capacities and administrative skills of the IMGGE staff and d) to become a regional leader in innovations tackling NDDs. Objectives will be achieved through networking, staff exchanges, training, summer schools, symposia, workshops, participation at conferences and dissemination in scientific community, industries and public. Twinning with partners will provide access to new research avenues, creativity, development of new approaches and increased mobility (inwards and outwards) of qualified scientists.