Health Disparities in Alzheimer's Disease: Intergenerational and Sociocultural Contributors to Dementia Literacy in Immigrant Latinx Families

项目摘要 西班牙裔移民老年人患阿尔茨海默病和相关痴呆的风险更大 (ADRD)，并带来不成比例的更重的相关并发症负担。建议数 这项研究最终旨在通过绘制痴呆症识字体系结构来减轻这一负担(即， 关于病因、治疗和对疾病的态度的知识)和确定 文化上特定的疾病认知，可用于未来的干预研究。 目前，标准的早期ADRD疾病检测对拉丁裔移民缺乏足够的有效性 老年人由于缺乏以证据为基础的科学，将文化和社会差异纳入 帐号。通过一项旨在为未来假设提供试点数据的横断面设计- 在其他移民群体中推动干预研究，拟议的研究将显著扩大 目前移民中的痴呆症识字知识基础。一种新颖的、基于家庭的招聘 以有移民祖父母的大学生为中心的办法将适用于200人 用于收集问卷和基于调查的痴呆症评估的拉丁裔成年人 识字和一系列社会文化因素，如适应文化、移民 熟练掌握英语/西班牙语的经验和学位。拟议的研究 环境非常适合这项提议的成功。皇后学院是西班牙裔 服务机构和周围社区是最大的集中地 纽约州的移民。《首席调查员》有一段文化认知史 在包括痴呆症在内的一些疾病州进行调查，并将利用拟议的 学习以推动她在皇后学院的独立。合作调查员莫妮卡·里维拉·明特博士 是拉丁裔健康差异方面的专家，资助完成对艾滋病毒+痴呆症风险的研究 拉丁裔长辈，并有与申请者成功合作的历史。 。

Project Summary Hispanic immigrant elders are at greater risk for Alzheimer’s disease and related dementias (ADRD) and carry a disproportionately heavier burden of related complications. The proposed study ultimately aims to reduce this burden by mapping the architecture of dementia literacy (i.e., knowledge about the causes, treatments and attitudes towards the disease) and identifying culturally-specific disease perceptions that can be utilized for future interventional studies. Currently, standard early ADRD disease detection lacks adequate validity for Latinx immigrant elders due to the absence of evidence-based science that take culture and social disparities into account. Through a cross-sectional design purposed to supply pilot data for future hypothesis- driven intervention studies in other immigrant groups, the proposed study will significantly expand the current dementia literacy knowledge base in immigrants. A novel, family-based recruitment method, centered on college students with immigrant grandparents, will be applied to enroll 200 Latinx adults for the collection of questionnaires and survey-based assessments of dementia literacy and a comprehensive panel of sociocultural factors such as acculturation, immigration experience and degree of English/Spanish language proficiencies. The proposed research environment is ideally suited for the success of this proposal. Queens College is a Hispanic Serving Institution and the surrounding community is home to the largest concentration of immigrants in New York State. The Principle Investigator has a history of cultural cognitive investigations in a number of diseased states, including dementia, and will utilize the proposed study to propel her independence at Queens College. Co-investigator, Dr. Monica Rivera-Mindt, is an expert in Latinx health disparities, funded to complete research on dementia risk in HIV+ Latinx elders and has a history of successful collaboration with the applicant. .