Social determinants of sleep and obesity: Disparities in African Americans

项目总结/摘要 这项拟议中的研究旨在通过促进健康的生活方式来减少与肥胖相关的健康差距， 非裔美国人（AAs）的死亡率，考虑到与低体力活动相关的高疾病负担， 充足的睡眠和肥胖。为此，候选人将寻求了解社会背景因素如何 通过使用定性访谈和现有的定量数据集（K99）影响睡眠。获得的知识 将告知现有睡眠干预的适应和测试（MDACC IRB Proto- col #2018-0568）（R00）。在K99阶段，候选人将接受重点和密集的培训，包括- 举办研讨会、课程、讲座，并指导健康护理领域知名专家的阅读， 领带，安眠药，和肥胖症两项研究将包括：（目标1）进行定性深入访谈， 阐明社会背景对睡眠的影响，同时征求反馈，以适应睡眠干预， 肥胖、久坐和睡眠时间短的AA成年人;以及（目的2）经验性地测试如此- 社会背景因素、睡眠、体力活动和体重，使用来自正在进行的AA研究的数据 （项目FAITH;美国癌症协会，RSG-17-158-01; PI：麦克尼尔博士，导师）。在R 00期间 阶段将汇编K99阶段获得的知识，以适应睡眠干预并测试其可行性， 满意度，以及改善睡眠，增加体力活动和减少久坐的初步疗效 超重/肥胖、久坐和睡眠不足的AA成年人的行为（目标3）。候选人是 根据他过去在治疗insom方面的临床经验， nia和他对AA中睡眠和肥胖的研究。睡眠干预是一个有前途的创新 优化心理和身体健康以减少肥胖和癌症相关健康疾病的方法 平等-国家少数民族健康和健康差距研究所的一项优先研究。此外，委员会认为， 拟议的培训计划对于加快候选人向独立调查员的过渡至关重要 在制定文化知情干预措施以减少癌症健康差异方面具有专门知识 在AA之间。

PROJECT SUMMARY/ABSTRACT The proposed research aims to reduce obesity-related health disparities by promoting healthy lifestyle behav- iors among African Americans (AAs), given the high disease burdens associated with low physical activity, in- sufficient sleep, and obesity. To this end, the candidate will seek to understand how social contextual factors impact sleep by using qualitative interviews and an existing quantitative data sets (K99). Knowledge gained from the K99 phase will inform the adaptation and testing of an existing sleep intervention (MDACC IRB Proto- col #2018-0568) (R00). During the K99 phase, the candidate will receive focused and intensive training involv- ing workshops, courses, lectures, and directed readings from renowned experts in the fields of health dispari- ties, sleep medicine, and obesity. Two studies will include: (Aim 1) conducting qualitative in-depth interviews to elucidate social contextual influences on sleep, while soliciting feedback to adapt a sleep intervention among obese, sedentary, and short-sleeping AA adults; and (Aim 2) empirically testing the associations between so- cial contextual factors, sleep, physical activity, and body weight using data from an ongoing studies of AAs (Project FAITH; American Cancer Society, RSG-17-158-01; PI: Dr. McNeill, mentor). Lastly, during the R00 phase will compile the knowledge gained in the K99 phase to adapt a sleep intervention and test its feasibility, satisfaction, and preliminary efficacy in improving sleep, increasing physical activity, and decreasing sedentary behavior among overweight/obese, sedentary, and sleep-deprived AA adults (Aim 3). The candidate is uniquely positioned to complete the proposed research based on his past clinical experience in treating insom- nia and his research on sleep and obesity among AAs. The sleep intervention is a promising and innovative approach to optimizing psychological and physical wellness to reduce obesity and cancer-related health dis- parities – a research priority at the National Institute on Minority Health and Health Disparities. Furthermore, the proposed training plan will be critical in expediting the candidate’s transition to an independent investigator with focused expertise in developing culturally informed interventions to reduce cancer health disparities among AAs.