Dissemination and Implementation Science in Cardiovascular Outcomes (DISCO)

项目摘要/摘要 目标：此应用程序的目标是培训一批传播和实施(D&I)学者 使用严格的定性和定量方法从事T4翻译研究 采用、吸收、可接受性、可负担性、保真度和可持续性 建立了影响心肺、血液疾病和睡眠障碍(HLBS)的实施框架。 研究性职业发展计划的理论基础和设计：D&I领域的学者培训 研究涉及38名导师，他们在混合方法/评估、实用临床等领域具有专业知识 试验、卫生服务研究/结果、卫生政策。导师还具有特定领域的专业知识。 这样的社区参与、健康差距、测量、流行病学、卫生经济学。每个人 奖学金获得者将至少有两名导师，其中至少一名来自研究轨道，一名来自特定临床 焦点。学者必须同时获得知识和调查技能，并完成一系列工作 重要到足以证明其作为一名调查员的能力。这一计划是精心制定的，以允许 学者们需要获得成为独立调查人员所需的技能。 培训计划中的关键活动。我们提供了一个教学课程，其中包含特定的元素 是为这个项目设计的。本课程涉及的核心能力包括：(A)关于 传播和实施研究和评价的理论和概念，包括混合 方法和准实验设计(例如，阶梯形、自适应设计)；以及(B)关于 研究设计和方法所依据的理论和概念。我们重点介绍了成功用于 其他培训计划，以招募和挑选学者，以及评估学者的进展和指导 经验和指导的有效性。 计划任期：2-3年 预计学者人数：5人 预期奖学金获得者结果：参加K12计划后，奖学金获得者将有望获得 NIH或其他资助机构授予的年轻/新研究员或现有研究员奖。远程 目标是确保提供足够的训练有素的研究人员来应对HLBS的临床问题 通过精心设计、巧妙操作和多学科的临床研究来学习医学。

Project Summary/Abstract Objectives: The goal of this application is to train a cohort of dissemination and implementation (D&I) scholars to engage in T4 translational research using rigorous qualitative and quantitative methods to examine the adoption, uptake, acceptability, affordability, fidelity, and sustainability of proven-effective interventions using established implementation frameworks to impact heart, lung, and blood diseases and sleep disorders (HLBS). Rationale and design of the research career development program: The training of scholars in D&I research involves 38 mentors with expertise in area such as mixed methods/evaluation, pragmatic clinical trials, health services research/outcomes, health policy. The mentors also have specific expertise in areas such community engagement, health disparities, measurement, epidemiology, health economics. Each scholar will have at least two mentors, with at least one from the research track and one from a specific clinical foci. Scholars must acquire both the knowledge and investigative skills as well as accomplish a body of work significant enough to demonstrate competence as an investigator. This program is carefully formulated to allow scholars to acquire the skills needed to become independent investigators. Key activities in the training plan. We provide a didactic curriculum that comprises elements specifically designed for this program. The core competencies addressed by this curriculum include: (a) knowledge of the theories and concepts underlying dissemination and implementation research and evaluation, including mixed methods and quasi-experimental designs (e.g., step-wedge, adaptive designs); and (b) knowledge of the theories and concepts underlying research designs and methods. We highlight methods used successfully for other training programs to recruit and select scholars as well as evaluate scholar progress and the mentoring experience and mentoring effectiveness. Planned duration of appointments: 2-3 years Projected number of scholars: 5 scholars Intended scholar outcomes: Following participation in the K12 program, scholars will be expected to obtain a young/new investigator or established investigator award from the NIH or another funding agency. Long-range goal is to ensure an adequate supply of well-trained researchers to confront the clinical problems HLBS medicine through well-designed, skillfully conducted and multidisciplinary clinical research.