Reducing Weight Stigma to Improve Long-Term Weight Loss

项目总结/摘要 我的长期职业目标是成为一名独立的调查员， 治疗肥胖症的研究作为一名临床心理学家，我之前的训练集中在识别和 减少肥胖的有害心理社会后果，包括基于体重的耻辱。但为了 实现我的目标，进行研究，以减少不利的健康后果，提高生活质量， 对于肥胖症患者，我必须接受肥胖症临床治疗方面的额外培训。K23 如果我获得了这个奖项，我将能够投入90%的精力来填补我在培训中的关键空白， 这将有助于我成为一名独立的肥胖症临床研究者。 拟议的培训计划将通过解决三个基本领域来支持我的职业目标： 进行肥胖治疗的临床试验; 2）评估和促进研究参与者参与 体力活动; 3）了解增加心脏代谢疾病风险的生物学机制。我 将通过以下方式获得这些领域的培训：接受该领域专家导师的指导;完成 课程和参加研讨会;并从事相关的研究活动。这个训练计划会让我 在K23奖励期结束前准备成功的R 01申请所需的知识和技能。 我的研究项目将补充我的培训目标，同时也建立在我以前的耻辱- 相关的研究工作。在一项随机对照试验中，我将测试长期减肥的效果， 一种新的临床干预措施，旨在帮助肥胖者科普体重耻辱，结合。 标准行为减肥我相信，减少WBI将改善长期减肥，增加 体育活动，一种与长期减肥效果更好相关的行为。本研究项目 还将纳入心脏代谢风险评估，以确定降低WBI是否有助于改善 身体健康拟议的研究项目可能对增强 治疗肥胖和减少体重耻辱的负面影响。 宾夕法尼亚大学体重和饮食失调中心的环境 （宾夕法尼亚大学）是支持我的培训和研究需求的理想选择。该中心将提供实用资源， 数据管理和参与者招募、评估和治疗。我将主要接受指导 中心主任托马斯瓦登博士发来的额外的指导和研究资源将 由约翰·亚基奇博士（大学体育活动和体重管理中心主任）提供 匹兹堡教育学院）和丹尼尔雷德博士（宾夕法尼亚预防心血管疾病中心主任 程序）。除了这些特定中心之外，我还可以参加宾夕法尼亚大学的其他几个学术项目， 支持我的培训需求，包括糖尿病、代谢和肥胖研究所。佩恩提供了一个 非常丰富的环境，这将使我能够实现我的研究和培训目标。

PROJECT SUMMARY/ABSTRACT My long-term career goal is to be an independent investigator with a multidisciplinary program of research in the treatment of obesity. As a clinical psychologist, my prior training has focused on identifying and reducing harmful psychosocial consequences of obesity, including weight-based stigma. However, in order to achieve my goal of conducting research to reduce adverse health consequences and improve quality of life for persons with obesity, it is essential that I have additional training in the clinical treatment of obesity. The K23 award would enable me to devote 90% of my effort to filling critical gaps in my training and to conducting research that will facilitate my becoming an independent clinical investigator in obesity. The proposed training plan will support my career goals by addressing three fundamental areas: 1) conducting clinical trials in obesity treatment; 2) assessing and promoting study participants' engagement in physical activity; and 3) understanding biological mechanisms that increase risk for cardiometabolic disease. I will obtain training in these areas by: receiving guidance from expert mentors in the field; completing coursework and attending seminars; and engaging in related research activities. This training plan will give me the knowledge and skills needed to prepare a successful R01 application by the end of the K23 award period. My research project will complement my training objectives while also building upon my prior stigma- related research efforts. In a randomized controlled trial, I will test the effects on long-term weight loss of a novel clinical intervention designed to help individuals with obesity cope with weight stigma, combined with . standard behavioral weight loss. I believe that reducing WBI will improve long-term weight loss by increasing physical activity, a behavior consistently associated with greater long-term weight loss. This research project will also incorporate assessments of cardiometabolic risk to determine whether reducing WBI helps to improve physical health. The proposed research project could have significant clinical implications for enhancing the treatment of obesity and reducing the negative effects of weight stigma. The environment at the Center for Weight and Eating Disorders at the University of Pennsylvania (Penn) is ideal for supporting my training and research needs. The Center will provide practical resources for data management and participant recruitment, assessment, and treatment. I will receive mentorship primarily from Dr. Thomas Wadden, the Center's director. Additional mentorship and research resources will be provided by Dr. John Jakicic (director of the Physical Activity and Weight Management Center at the University of Pittsburgh School of Education) and Dr. Daniel Rader (director of the Penn Preventive Cardiovascular Program). Outside of these specific centers, I will have access to several other academic programs at Penn to support my training needs, including the Institute for Diabetes, Metabolism, and Obesity. Penn provides a remarkably rich environment that will enable me to achieve my research and training goals.