Metabolic Tissue Function

摘要：代谢组织功能核心 代谢组织功能核心的目的是提高糖尿病相关研究的效率 通过提供专业知识、设备和服务来优化糖尿病的研究能力 研究中心(DRC)成员。核心促进高质量的啮齿动物和人类小岛的获取和 协助研究人员开发诱导多能干细胞。此外，该核心还提供以下服务 与糖尿病及其发病机制相关的胰岛等代谢组织的功能分析 并发症。这些功能研究包括激素分泌分析，β细胞质量的评估， 代谢的量化，以及内质网应激和氧化应激途径的评估。 核心提供的专业知识和最先进的设备提高了专注于研究的效率 关于提高糖尿病的诊断、治疗和治愈水平。

ABSTRACT: Metabolic Tissue Function Core The purpose of the Metabolic Tissue Function Core is to improve the efficiency of diabetes-related research through provision of expertise, equipment, and services that optimize the investigational capacity of Diabetes Research Center (DRC) members. The Core facilitates acquisition of high quality rodent and human islets and assists investigators in developing induced pluripotent stem cells. In addition, the Core provides services for the functional analyses of islets and other metabolic tissues relevant to the pathogenesis of diabetes and its complications. These functional studies include hormone secretion assays, assessment of β-cell mass, quantification of metabolism, and assessment of endoplasmic reticulum stress and oxidative stress pathways. The expertise and state-of-the-art equipment provided by the Core improve the efficiency of research focused on improving the diagnosis, treatment and cure of diabetes.