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中文摘要
翻译
摘要 计划中的会议的目的是促进基于拉曼光谱的临床应用的发展。 阳离子。 拉曼散射为成像提供了无标记的对比度,这种对比度源于固有的分子振动。 由于它是无标签的,并且以公正的方式报告样本中的所有分子物种,因此它提供了全面的 观察临床样本中的化学环境,因此具有显著的fi诊断和诊断价值 治疗监测工具。 而拉曼散射现象早在1920年就已为人所知,其临床应用潜力也一直很大。 认识到几十年来,路障,包括微弱的信号水平和读出的复杂性,已经排除了 从临床上使用。这些障碍现在正通过仪器开发和创新来消除 机器学习。
英文摘要
Summary The purpose of the planned conference is to facilitate development of Raman-spectroscopy based clinical appli- cations. Raman scattering provides label-free contrast for imaging that derives from intrinsic molecular vibrations. Because it is label-free and reports in an unbiased way on all molecular species in a sample, it provides a holistic “view” of the chemical environment in clinical samples, and thus holds significant value as a diagnostic and treatment monitoring tool. While the phenomenon of Raman scattering has been known since 1920, and its clinical potential has been recognized for many decades, roadblocks including weak signal levels and complexity of its readout has precluded it from clinical use. These roadblocks are now being removed through innovations in instrument development and machine learning.
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Label-Free Cell-Resolved Metabolomics for Tumor Microscopy
  • 批准号:
    10359777
  • 项目类别:
  • 资助金额:
    $13.83万
  • 财政年份:
    2020
  • 负责人:
    Marcus T Cicerone
  • 依托单位:
海外基金