University of Colorado Cancer Center Support Grant

摘要 科罗拉多大学癌症中心（UCCC）推动癌症发现和创新，将这些 研究结果的临床，导致以病人为中心的护理，减少健康差距，培养下一代的 癌症为重点的科学家，并努力优化对我们的集水区的影响-科罗拉多州。 UCCC受益于资金的慷慨增加，并对所有项目进行了大量投资 和结构。最近取得的主要进展包括：（1）完成和部署一个全面的 战略计划; 2）重组方案; 3）招聘有活力和有成就的新领导人，包括 一名主任（舒利克）和一名第二副主任（布拉德利），以及招聘首届副主任 社区外展和参与，以及信息学和数据科学; 4）建立两个 癌症与衰老和癌症与代谢的交叉主题;以及5）UCCC成员资格的改革 委员会还建议制定标准，以更好地集中成员的活动，并更加强调辅导。这种大量注入的 资源和结构调整更好地使实验室的多项创新发现能够 通过临床试验、FDA批准和建立新的护理标准， 它们还促成了成功的双向社区外联和参与以及基于人口的 在流域内的方案，继续注重增加包容性和多样性。物理空间， 组织能力，跨学科合作和协调，癌症焦点，以及机构 所有的资源都得到了改善，使UCCC走上了成功的轨道。未来 在资助期间，UCCC将专注于战略目标，目标以及21项具体战略， 战略计划。这些战略的重点包括努力：1）提供优秀的研究基础设施 2）扩大临床研究、临床试验和制药商发起的试验; 3)扩大跨项目的研究和干预，以解决健康结果、差距和服务不足问题 4）培养未来的肿瘤学研究人员，临床医生和管理人员的管道; 加强UCCC内部和所有站点之间的协调与合作;以及5）增加慈善支持。 如有必要，UCCC领导将修改课程，以适应意想不到的挑战（例如，COVID）和 机会（例如，建立数据科学的校园倡议）。

ABSTRACT The University of Colorado Cancer Center (UCCC) drives cancer discovery and innovation, translates these findings to the clinic, leads in patient-centered care, reduces health disparities, trains the next generation of cancer focused scientists, and strives to optimize the impact on our catchment area – the State of Colorado. UCCC has benefited from a generous increase in funding and has made significant investments into all programs and structures. The highlights of recent progress include: 1) completion and deployment of a comprehensive strategic plan; 2) restructure of the programs; 3) recruitment of dynamic and accomplished new leaders including a Director (Schulick) and a second Deputy Director (Bradley), and recruitment of inaugural Associate Directors of Community Outreach and Engagement, as well as Informatics and Data Science; 4) establishment of two cross cutting themes of Cancer and Aging and Cancer and Metabolism; and 5) overhaul of UCCC membership criteria to better focus the activities of members and to increase emphasis on mentoring. This large infusion of resources and restructuring have better enabled multiple innovative discoveries in the laboratories to be brought to the bedside through investigator-initiated trials, FDA approval, and establishment of new standards of care. They have also enabled successful bi-directional community outreach and engagement and population-based programs within the catchment, with continued focus on increasing inclusion and diversity. The physical space, organizational capabilities, transdisciplinary collaboration and coordination, cancer focus, and institutional resources have all been improved, setting UCCC on a trajectory of success well into the future. In the next funding period, UCCC will focus on the strategic aims, goals, as well as the 21 specific strategies outlined in the strategic plan. Highlights of these strategies include efforts to: 1) provide outstanding research infrastructure and state-of the art shared resources; 2) expand clinical research, clinical trials and investigator-initiated trials; 3) expand research and interventions across programs to address health outcomes, disparities, and underserved populations; 4) nurture the pipeline of prospective oncology researchers, clinicians, and administrators; strengthen alignment and collaboration within the UCCC and across all sites; and 5) grow philanthropic support. As necessary, UCCC leadership will modify the course to adjust to unexpected challenges (e.g., COVID) and opportunities (e.g., campus-wide initiative to build data science).