University of Colorado Cancer Center Support Grant - CTRAC Supplement Yr 02

项目摘要/摘要 临床研究的开展对于改善癌症患者的治疗选择至关重要。许多 治疗方案很复杂，并且使用电子健康记录系统开出处方，其中治疗 以前已经建立了协议订单。建立这些治疗方案的工作是复杂的 这一过程涉及多个步骤，耗费大量时间，可能是开启临床试验的限制步骤。多臂 而协议修改的构建可能特别耗时。不幸的是，对于多点临床试验， 这一建立过程在每个站点重复，表示在整个临床研究中缺乏效率 系统。该项目寻求将一个由NCI指定的癌症中心组成的联盟聚集在一起，这些中心是领导者 在进行临床研究和临床信息学方面，以及与EHR公司的协调下， 建立标准化的构建约定，开发使临床试验方案构建可互操作的方法 跨站点，并最终使临床研究的进行大大提高效率。以这种方式 我们将能够更好地利用临床信息学系统的力量来加快临床工作的进行 癌症研究。

Project Summary / Abstract The conduct of clinical research is essential to improving the treatment options of cancer patients. Many treatment protocols are complex and prescribed using electronic health record systems where the treatment protocol orders have been built previously. The work of building these treatment protocols is a complex process involving many steps, substantial time, and can be the limiting step in opening clinical trials. Multi-arm and protocol amendments can be particularly time consuming to build. Unfortunately for multi-site clinical trials, this build process is duplicated at each site representing a lack of efficiency in the overall clinical research system. This project seeks to bring together a consortium of NCI-designated cancer centers who are leaders in both the conduct of clinical research and in clinical informatics, along with coordination with EHR companies, to establish standardized build conventions, develop means to make clinical trial protocol builds interoperable across sites, and ultimately to make the conduct of clinical research substantially more efficient. In this way we will be able to better leverage the power of clinical informatics systems to accelerate the conduct of clinical cancer research.