PHSU Specialized Center in Health Disparities.

总体汇总 PHSU经历了其人力和物理研究基础设施的重大发展。通过 在RCMI计划的支持下，PHSU能够招募顶尖人才，获得最先进的 设施，设备和其他资源，以追求有竞争力的基础，临床和行为 research.作为这一发展的直接影响，该机构大大受益于 在：同行评议的手稿的数量和质量引起的教师，数量的科学 在国家和国际两级竞争性论坛上的介绍，以及提交和 资助研究和研究培训活动。为了进一步开展这些工作，该机构提交了 目前的续约申请。其主要目标是促进高质量的翻译研究， 强调健康差距。本申请包括五项核心活动： 核心（AC），研究资源中心（CRR），战略学术研究培训（START）核心， 健康差异社区培训研究所（CTIHD）和教师招聘（FR）核心。的 AC旨在带头采取一系列举措，旨在加强该机构作为一个强大的， 充满活力的翻译研究中心，并进一步发展我们的研究人员成为独立的， 胜任的生物医学研究人员。这些举措包括组织和启动;专业 发展活动和建立新的研究伙伴关系和协作。开始 核心建议发展参与少数民族健康和HD研究的早期研究人员， 实现建立多样化的国家劳动力队伍以实现保健平等的总体目标， 医疗结果。拟建的中央档案室旨在提供现代化的技术和设施， 在RCMI计划内开发研究项目、试点项目和核心项目。CTIHD 核心旨在建立一个创新的基础设施，通过加强 RCMI/PHSU研究人员及其与社区成员的伙伴关系。拟议的FR核心 旨在招募和保留RCMI目标领域的生产力高生产力的研究人员; 癌症生物学/肿瘤学、神经科学、传染病、心血管/高血压研究，以及 人类遗传学。此外，目前的RCMI申请包含三个完整的研究项目（RO 1级）。 这个新的RCMI计划的拟议领导将使用多个PI选项。关键人员在 AC（Torres-Ruiz和诺埃尔博士以及安杜贾尔女士）将被授予必要的权力， 提出了RCMI计划的实施方案。此外，目前的高级行政当局 申请机构完全致力于拟议的RCMI的使命、目标和总体目标 与下一阶段提升机构研究竞争力的计划相一致的计划 在为期五年的资助周期中，拟议的RCMI计划包括一个综合评估计划。

OVERALL SUMMARY PHSU has experienced substantial development of its human and physical research infrastructure. Through auspices of the RCMI Program, PHSU has been able to recruit top-notch talent, acquire state-of-the-art facilities, equipment, and other resources required to pursue competitive basic, clinical, and behavioral research. As a direct impact of this development, the institution has greatly benefited from the improvement in: number and quality of the peer-reviewed manuscripts elicited by the faculty, number of scientific presentations at competitive forums at the national and international levels, and number of submitted and funded research and research training initiatives. In furthering with these efforts, the institution is submitting the present renewal application. Its main goal is to promote high-quality translational research with a strong emphasis on health disparities (HD). The present application consists of five Core activities; Administration Core (AC), Center for Research Resources (CRR), Strategic Academic Research Training (START) Core, the Community Training Institute for Health Disparities (CTIHD), and the Faculty Recruitment (FR) Core. The AC is intended to spearhead a series of initiatives designed to strengthen the institution as a robust and vibrant translational research center and to further develop our research faculty into independent and competent biomedical researchers. These initiatives include the organization and inception of; professional development activities and the establishment of new research partnerships and collaborations. The START Core proposes the development of early-stage investigators involved in minority health and HD research to address the overarching goal of providing for a diverse national workforce to bring parity to health and healthcare outcomes. The proposed CRR is designed to provide modern technologies and facilities to support the development of the research projects, pilot projects, and Cores within the RCMI program. The CTIHD Core is intended to establish an innovative infrastructure for promoting HD research through the strengthening of RCMI/PHSU researchers and their partnerships with community members. The proposed FR Core has been designed to recruit and retain productive highly productive research faculty in RCMI targeted areas; Cancer Biology/Oncology, Neurosciences, Infectious Diseases, Cardiovascular/Hypertension research, and Human Genetics. Moreover, the present RCMI application contains three full research projects (RO1 level). The proposed leadership for this new RCMI Program will use the multiple PIs option. The key personnel at the AC (Drs. Torres-Ruiz and Noel, and Ms. Andujar) will be empowered with the necessary authority to carry out the RCMI Program implementation plan as proposed. Moreover, current upper administration at the applicant institution is fully committed to the mission, goals, and general objectives of the proposed RCMI Program consonant to the plans of elevating the research competitiveness of the institution during the next five-year funding cycle, the proposed RCMI Program includes a Comprehensive Evaluation Program.