Core C: Community Engagement Core

项目摘要/摘要-社区参与核心 N-亚硝胺是一类化学物质，其中包括一些已知的最强的诱变剂。N-亚硝胺 是居住在奥林化学超级基金网站附近的人的主要担忧，因为那里有一缕N- 亚硝基二甲胺(NDMA)对地下近一英里的水和土壤的污染， 污染市政和私人水井。NDMA也是PassamAquoddy部落的一个关切，因为 众所周知，水处理方法会导致NDMA的形成。多年来，麻省理工学院的团队 在信任和共同目标的基础上建立了牢固的关系，这些关系是 正在进行的和拟议的工作。通过与利益相关者的双向沟通和协作，CEC 在完成其环境健康科学教育青年的使命方面发挥了至关重要的作用，鼓舞人心 为下一代科学家的研究事业和社会责任，并减少N- 饮用水中的亚硝胺。具体目标1是教书。与BMR项目1和2合作，CEC将 创造创新的实践学习体验，传授生物学和环境的关键概念 健康科学。与部落教育者(文化守护者)合作，麻省理工学院团队将共同创建和分发 实践体验学习包，向部落青年传授生物学和环境健康的关键概念。 CEC还将与威尔明顿的高中教师合作，优化实践教学体验 威尔明顿高中教师分享与麻省理工学院SRP项目研究重点相关的知识1 2.使用触觉教学工具包，麻省理工学院SRP将通过共同创建和提供 向未被充分代表的少数群体(URM)提供教学经验，以激励他们在环境健康领域的事业。 具体目标2是通过与所有项目合作来干预和预防疾病，以增强利益攸关方的能力 以降低有害物质的水平和毒性。CEC将与社区合作 利益攸关方与包括环境保护局在内的能够帮助提供更清洁水的组织更好地沟通。 此外，为了减少毒物水平，CEC(在环境科学和环境科学的支持下) 工程[ESE]项目3和4)，将与一个培养未来领导者的非营利性组织合作 在工业化学中采取减少和防止环境污染的策略。特定目标 3是支持使用由ESE项目3和4开发的技术来执行公民 科学，并为社区提供过滤设备。关于N-的身份和水平的数据- 亚硝胺将由CEC通过公民科学项目与社区成员合作收集。 关于N-亚硝胺水平的数据将与其他项目和核心的数据结合起来，以作出贡献。 风险评估。CEC还将帮助部署一种新型的过滤设备，以摧毁N-亚硝胺。通过 通过让人们了解他们的水中有什么，并提供过滤设备，CEC将减少 饮用水中危险化学品的含量和毒性。

PROJECT SUMMARY/ABSTRACT – COMMUNITY ENGAGEMENT CORE N-Nitrosamines are a family of chemicals that include some of the most potent mutagens known. N-nitrosamines are a major concern for people who live near the Olin Chemical Superfund Site, because there is a plume of N- nitrosodimethylamine (NDMA) contamination of water and soil that stretches nearly a mile underground, contaminating municipal and private wells. NDMA is also a concern of the Passamaquoddy Tribe, because the methods used for water treatment are known to lead to formation of NDMA. Over many years, the MIT team has created strong relationships based on trust and mutually shared goals, and these relationships are the basis for ongoing and proposed work. Via bi-directional communication and collaboration with stakeholders, the CEC plays a vital role in accomplishing its mission of educating youth in environmental health sciences, inspiring research careers and social responsibility for the next generation of scientists, and reducing the amount of N- nitrosamines in drinking water. Specific Aim 1 is to teach. Working with BMR Projects 1 and 2, the CEC will create innovative, hands-on learning experiences that teach key concepts of biology and environmental health sciences. Working with the tribal educators (Culture Keepers), the MIT team will co-create and distribute hands-on experiential learning kits to teach key concepts of biology and environmental health to Tribal Youth. The CEC will also work with high-school teachers in Wilmington to optimize hands-on teaching experiences for Wilmington high-school teachers to share knowledge related to the research focus of the MIT SRP Projects 1 and 2. Using tactile teaching kits, the MIT SRP will address the pipeline problem by co-creating and offering teaching experiences to underrepresented minority (URM) individuals to inspire careers in environmental health. Specific Aim 2 is to intervene and prevent disease by working with all Projects to empower stakeholders to reduce the levels and toxicity of hazardous substances. The CEC will partner with community stakeholders to better communicate with organizations that can help to provide cleaner water, including the EPA. In addition, to reduce the levels of toxicants, the CEC (with support from the Environmental Science and Engineering [ESE] Projects 3 and 4), will team up with a non-profit organization that teaches tomorrow's leaders in industrial chemistry to adopt strategies that reduce and prevent environmental contamination. Specific Aim 3 is to support the use technology that will be developed by ESE Projects 3 and 4 to perform Citizen Science and provide filtration devices to the community. Data on the identity and the levels of N- nitrosamines will be collected by the CEC in collaboration with community members via a Citizen Science project. Data on the levels of N-nitrosamines will be integrated with data from the other Projects and Cores to contribute to risk evaluation. The CEC will also help to deploy a novel filtration device that destroys N-nitrosamines. By empowering people with knowledge of what is in their water and by offering filtration devices, the CEC will reduce the amount and toxicity of hazardous chemicals in drinking water.