University of Minnesota Clinical and TranslationalmScience Institute (UMN CTSI)

联系PD/PI：Blaazar，Bruce 答：总体来说：抽象。明尼苏达大学临床与翻译科学研究所(UMN CTSI)视觉是这样一个世界，在这个世界里，导致人类健康改善的有影响力的发现发生在 将学术卫生中心(AHC)研究与社区推广和行业相结合 伙伴关系。我们的使命是创建一个全国公认的、可共享的复杂翻译团队模式 临床和转化科学(CTS)研究的整合和调整推动和推动了科学 教育、数据访问、社区需求和行业努力。在过去的6年里，CTSI 1)发展了 为下一代员工提供全面的劳动力培训和职业发展计划 CTS研究人员；2)创建社区参与以推动研究和社区 健康(CEARCH)，支持利益相关者社区对CTS研究的贡献，并解决健康问题 索马里人、拉丁裔、美洲原住民、苗族和其他人群的结果差异挑战；3) 利用UMN的研究优势和MN充满活力的生物医药产业推动多个项目 商业化途径；4)扩大其患者基础，从UMN三级护理成人和 儿科医院到枢纽合作伙伴，由退伍军人医院、基于社区的7家医院系统和 安全网县医院，65%的种族/少数民族与i2b2/shine相连，用于队列识别。 CTSI与Mayo CTSA建立了史无前例的合作伙伴关系，在CTS提供全州覆盖 是中西部地区健康研究联盟的创始成员之一 临床试验联合队列发现联盟和PCORnet大平原合作组织的收益。 为了加快和改进CTS研究和教育，并对医疗保健成果产生持久影响， 我们将追求以下目标：1.培养一支跨领域、多元化的优秀劳动力队伍 CTS研究谱精通团队科学，并利用现有的和新的教育 提供服务；2.简化方法和流程，以提高地方和国家CTSI中心的研究能力 在一个新的诊所和外科中心学习健康系统与CTSI主导的研究流程设计，CTSI的 新的StudyFinder工具，用户友好的IRB批准的临床和实验室研究同意书，生物信息- Matics工具、生物样品收集和一站式变革性临床研究支持中心， 单一地点，并行处理所需审批；3.通过以下方式与社区和利益攸关方接触 CEARCH改善翻译和向不同人群提供的医疗保健服务；以及 4.增加儿科发现和翻译办公室对CTSA网络的独特贡献 设备创新联盟，高和超高磁共振成像和光谱分析 申请和培训。冲击力。与其愿景和使命相联系并在其推动下，CTSI将提供 基础设施和服务，用于开展创新、高影响、高效、高质量的CTS研究。 项目摘要/摘要页391 联系PD/PI：Blaazar，Bruce

Contact PD/PI: Blazar, Bruce A. Overall: Abstract. The University of Minnesota's Clinical and Translational Science Institute's (UMN CTSI) vision is a world where impactful discoveries leading to the betterment of human health occur by bringing together Academic Health Center (AHC) research with community outreach and industry partnership. Our mission is to create a nationally-recognized, shareable model of complex translational team science driven and enabled by integration and alignment of clinical and translational science (CTS) research with education, data access, community needs, and industry efforts. In the past 6 years, CTSI 1) Developed comprehensive programs for workforce training and fostering career development for the next generation of CTS research investigators; 2) Created Community Engagement to Advance Research and Community Health (CEARCH) to support stakeholder community contributions to CTS research and to tackle health outcome disparity challenges in Somali, Latino, Native American, Hmong, and other populations; 3) Leveraged UMN research strengths and MN's vibrant biomedical industry to advance multiple projects along the commercialization pathway; and 4) Expanded its patient base from the UMN tertiary care adult and pediatric hospitals to hub partners consisting of a VA hospital, a community-based 7-hospital system, and a safety-net county hospital with 65% racial/ethnic minorities linked with i2b2/SHRINE for cohort identification. CTSI formed an unprecedented partnership with Mayo CTSA to provide statewide coverage in CTS research and education and is a founding member of the Midwest Area Research Consortium for Health, the Accrual to Clinical Trials federated cohort discovery consortium, and PCORnet Greater Plains Collaborative. To accelerate and improve CTS research and education and make lasting impacts on healthcare outcomes, we will pursue the following aims: 1. Train an outstanding multidisciplinary, diverse workforce across the CTS research spectrum skilled in and rewarded for team science using existing and new educational offerings; 2. Streamline methods and processes to increase local and national CTSI hub research capacity in a new Clinics and Surgery Center learning health system with CTSI-led research process design, CTSI's new StudyFinder tool, user-friendly IRB-approved consent form for clinical and laboratory research, bioinfor- matics tools, biospecimen collection, and a transformative Clinical Research Support Center for one-stop, single location, parallel processing of needed approvals; 3. Engage communities and stakeholders through CEARCH to improve translation and healthcare delivery across the lifespan and to a diverse population; and 4. Add unique contributions to the CTSA network by the Office of Discovery and Translation , Pediatric Device Innovation Consortium, and high and ultrahigh magnetic resonance imaging and spectroscopy applications and training. Impact. Connected to and driven by its vision and mission, CTSI will provide infrastructure and services for conducting innovative, high-impact and efficient, high-quality CTS research. Project Summary/Abstract Page 391 Contact PD/PI: Blazar, Bruce