Enhancing patient and organizational readiness for cardiovascular risk reduction among ethnic minority patients living with HIV

项目摘要/摘要 针对NOT-OD-21-020，特别关注通知：研究行政补编 和与生物伦理问题相关的能力建设努力，这项创新的提案旨在进行 促进黑人和拉丁裔公平制定新冠肺炎疫苗决策的生物伦理研究 艾滋病毒携带者(PLWHIV)和心血管疾病(CVD)风险。以减轻不成比例的影响 除了针对有色人种社区的COVIID-19疫苗外，新冠肺炎疫苗必须迅速到达最需要的人手中。 然而，疫苗的犹豫不决和无法获得可靠的新冠肺炎信息泄露了消息 决策，减少公平和公平地获得新冠肺炎疫苗和抑制疫苗 易受伤害亚群的摄取。这项提案旨在扩大公共卫生的覆盖范围 信息(例如，新冠肺炎疫苗教育倡议公共卫生工具包和社区 对抗新冠肺炎的接洽联盟(CEL)，通过互动会话承认 新冠肺炎疫苗关注、支持讨论犹豫不决的根源，并促进公平 在多种价值观(例如，个人、身体、公共)的背景下获得可靠的信息 这影响了新冠肺炎疫苗的决策。具体目标是：1)评估一项 关于了解、获取和信任可靠的新冠肺炎公共卫生信息的虚拟会议 在60名感染艾滋病毒并有患心血管疾病风险的HHMB参与者(20名西班牙人)中，2)确定了新冠肺炎 疫苗关注具体与艾滋病毒和心血管疾病风险有关，3)确定虚拟 HHMB参与者认为他们有足够的信息来制造新冠肺炎的会议 疫苗决定，新冠肺炎的决定，以及决定是否接受冠状病毒感染- 19疫苗，以及4)评估个人、身体和公共价值的使用之间的关系 在虚拟课程中授课，做出新冠肺炎决策，并决定是否接受 新冠肺炎疫苗。这些目标将通过一次新颖的、文化上一致的会议来实现， 为注册的虚拟HHMB参与者推广新冠肺炎疫苗决策。 没有机会就个人和历史经历进行对话， 犹豫不决，并为增加对准确、清晰和 可理解的新冠肺炎公共卫生和疫苗信息，黑人和拉丁人PLWHIV和CVD 风险将继续缺乏做出新冠肺炎疫苗决策的公平性。配套新冠肺炎疫苗 决策方法将促进人口层面的疫苗接种，有助于缓解 在有色人种社区中，新冠肺炎发病率和死亡率的差异。调查结果将被细化到 为疫苗决策方法提供信息，以接触到其他易受伤害的亚群。

Project Summary/Abstract In response to NOT-OD-21-020, Notice of Special Interest: Administrative Supplement for Research and Capacity Building Efforts Related to Bioethical Issues, this innovative proposal aims to conduct bioethical research to promote equitable COVID-19 vaccine decision-making among Black and Latinx people living with HIV (PLWHIV) and cardiovascular (CVD) risk. To mitigate the disproportionate impact of COVIID-19 on communities of color, COVID-19 vaccines must quickly reach those in greatest need. However, vaccine hesitancy and lack of access to reliable COVID-19 information compromise informed decision-making, reducing equitable and fair access to COVID-19 vaccines and inhibiting vaccine uptake in vulnerable subpopulations. This proposal seeks to expand the reach of public health messages (e.g., The COVID-19 Vaccine Education Initiative Public Health Toolkit and The Community Engagement Alliance (CEAL) against COVID-19),with an interactive session that acknowledges COVID-19 vaccine concerns, supports discussion of sources of hesitancy, and facilitates equitable access to reliable information within the context of multiple values (e.g., personal, bodily, communal) that impact COVID-19 vaccine decision-making. The Specific Aims are to: 1) evaluate the effect of a virtual session on knowledge of, access to, and trust in reliable COVID-19 public health messages among 60 HHMB participants (20 Spanish) living with HIV and at risk for CVD, 2) identify COVID-19 vaccine concerns specifically related to HIV and CVD risks, 3) determine the impact of the virtual session on HHMB participants’ perception that they have adequate information to make a COVID-19 vaccine decision, making a COVID-19 decision, and whether or not the decision is to receive a COVID- 19 vaccine, and 4) evaluate the relationship between use of personal, bodily, and communal values taught in the virtual session, making a COVID-19 decision, and deciding whether or not to receive a COVID-19 vaccine. These aims will be addressed through a novel, culturally consistent session, “Promoting COVID-19 Vaccine Decision-Making (HHMB-PVDM) for enrolled virtual HHMB participants. Without the opportunity to engage in dialogue about personal and historical experiences that impact hesitancy and provide support for increasing knowledge of and access to accurate, clear, and understandable COVID-19 public health and vaccine information, Black and Latinx PLWHIV and CVD risks will continue to lack equity in making COVID-19 vaccine decisions. Supporting COVID-19 vaccine decision-making approaches will facilitate population-level vaccine uptake, contributing to the mitigation of disparities in COVID-19 morbidity and mortality in communities of color. Findings will be refined to inform vaccine decision-making approaches to reach other vulnerable subpopulations.