National Drug Early Warning System (NDEWS) Administrative Supplement - Poison Control

补助金和拟议补助金摘要 母研究：通过我们的母研究U01，我们的国家药物预警系统（NDEWS）协调 中心旨在为NIDA和该领域提供最及时，最突出和最有价值的信息， 物质使用趋势。通过扩大数据收集范围，包括以前的NDEWS哨点以及 前社区流行病学工作组（CEWG）的网站，并通过纳入新的监测方法 为了确保及早发现新的精神活性物质和已知物质的信号，我们的预警系统 网络扩展了地理表示，并提供了更完整的大小、方向和 在所有美国人口普查地区的物质使用模式的深度。我们使用新的监测方法，以确保早期 * 发现表明新出现的毒品趋势的信号，并统一各哨点和 CEWG研究中心。我们还将对紧急危机或紧急情况进行实地流行病学调查。 需要为受影响的社区提供功能反馈，以优化当前和未来 我们将迅速向科学界和公众传播研究结果。 拟议补编：作为预警系统，NDEWS必须站在毒品新趋势的最前沿 使用以及与毒品有关的发病率和死亡率。缺乏当前或最近与毒品有关的死亡率数据 因为死亡信息的处理要滞后数月。然而，毒物控制数据可以让我们 在48个州发现与吸毒有关的中毒和死亡（“暴露”）的新趋势， 真实的时间。我们将从滥用、转移和成瘾相关研究中心获得毒物控制数据。 监测系统，并审查与使用海洛因、芬太尼及其 类似物，可卡因，甲基苯丙胺和各种新的精神活性物质，按月计算，为期12个月， 以接近真实的时间提醒科学家和公众热点的趋势。费率将根据性别、人口普查 年龄组、影响的严重程度（即，无、轻微、中度、严重、死亡）、给药途径、意图 (e.g.,故意滥用、自杀企图）和合并用药。对于目标1，我们将获取毒物控制数据， 每月一次，并近实时地审查与毒品有关的接触和死亡的当前趋势。对于目标2， 将获取最早至2015年的数据，并回顾性地研究趋势。对于目标3，我们将迅速 向科学界和公众传播（每月）与毒品有关的接触统计数据 通过NDEWS名录服务和媒体宣传，并通过同行评审 出版物。我们相信这是一个快速和频繁分析药物暴露的非凡机会 数据和传播调查结果。

SUMMARY OF PARENT GRANT AND PROPOSED SUPPLEMENT Parent Study: Through our parent U01, our National Drug Early Warning System (NDEWS) Coordinating Center aims to provide NIDA and the field with the most timely, salient, and valuable information on emerging substance use trends. By expanding data collection to include both former NDEWS sentinel sites as well as former Community Epidemiology Workgroup (CEWG) sites, and by incorporating novel surveillance methods to ensure early detection of signals of new psychoactive substances and known substances, our Early Warning Network extends geographic representation and provides a more complete picture of the size, direction, and depth of substance use patterns in all US Census regions. We use novel surveillance methods to ensure early detection of signals indicating emerging drug trends and harmonize surveillance data across sentinel and CEWG sites. We will also conduct on-the-ground epidemiologic investigations on topics of immediate crisis or need in order to provide functional feedback to impacted communities towards optimizing current and future response, and we will disseminate results rapidly to the scientific community and the public alike. Proposed Supplement: As an Early Warning System, NDEWS must be on the forefront of new trends in drug use, and drug-related morbidity and mortality. There is a lack of current or recent drug-related mortality data because processing of death information is lagged by months. Poison Control data, however, would allow us to detect emerging trends in both poisonings and deaths (‘exposures’) related to drug use in 48 states in almost real time. We will obtain Poison Control data from the Researched Abuse, Diversion and Addiction-Related Surveillance (RADARS) System and examine trends in exposures related to use of heroin, fentanyl and its analogs, cocaine, methamphetamine, and various new psychoactive substances, by month, for 12 months, to alert scientists and the public about trends in hotspots in near real time. Rates will be based on sex, Census age group, severity of effects (i.e., none, minor, moderate, major, death), route of drug administration, intent (e.g., intentional misuse, suicide attempt), and co-drug use. For Aim 1, we will acquire Poison Control data, monthly, and examine current trends in drug-related exposures and deaths, in near-real-time. For Aim 2, we will obtain data going as far back as 2015 and examine trends retrospectively. For Aim 3, we will rapidly disseminate statistics (monthly) on drug-related exposures to the scientific community and to the public through NDEWS listservs and media outreach and disseminate retrospective trends through peer-reviewed publications. We believe this is an extraordinary opportunity to quickly and frequently analyze drug exposure data and disseminate findings.