Cancer Center Support Grant

项目总结 这 21-026“。 低- 柱头 癌症 癌症 宫颈 癌症 和 研究所 衡量标准 宫颈 耶鲁大学 这个 这 解释性的 有性 促进者 在……里面 有性 随机 探索 社区 委员 个人， 柱头 减缩 在… 申请是对特别利益通知(NOSI)的回应，该通知被确定为“非CA- 宫颈癌是世界上女性中最常见的癌症，其影响不成比例。 和中等收入国家，85%的宫颈癌病例发生在这些国家。癌症耻辱与性行为 可能是成功的癌症预防、筛查和治疗计划的障碍，破坏 护理连续不断，特别是宫颈癌筛查和治疗。子宫颈之间的联系 人类乳头状瘤病毒，一种常见的性传播感染(STI)，进一步使人们 癌症。因此，有必要了解癌症和性污名对子宫颈的影响。 筛查和治疗吸收，以制定干预措施，以产生耻辱和加强筛查 治疗。耶鲁大学实施和预防科学方法中心，与 尼泊尔加德满都大学实施科学与卫生研究所正在进行一项关于 可接受性、可行性、成本和可持续性，以及探索影响因素和障碍， 尼泊尔中部的癌症筛查和治疗，得到了这项补充的父母赠款的支持， 美国耶鲁大学癌症中心(YCC)P30 CA016359，《耶鲁综合癌症中心支持拨款》， 他的补充剂申请的首席研究员担任全球肿瘤学助理主任 研究工作进展顺利，为作为目前研究的平台，我们建议实施 用混合方法评估宫颈癌污名和其他交叉因素的影响 L对宫颈鳞癌的筛查摄取和伴侣披露，并探讨其驱动因素和 这样的耻辱。癌症污名量表和STI污名羞耻量表的使用 尼泊尔进一步研究癌症和癌症之间的预期联系 424人中接受和向男性伴侣披露宫颈癌筛查的耻辱 选定的30至60岁的妇女居住在尼泊尔中部的Dhulikhel市。目标2将 宫颈癌污名的驱动因素、促进者和表现 对有目的地选择的妇女(n=8)、家庭进行定性深入访谈 (n=8)和社区领导人(n=8)在卫生污名和歧视框架指导下 家庭、保健提供者和社区层面，旨在确定未来的有希望的组成部分 减量干预。这项研究将为今后的方案努力提供对关键因素的见解 在资源匮乏的情况下，提高宫颈癌筛查和治疗的机会，同时， 同时，进一步加强家长基金的全球肿瘤学计划。 C C R 。 AIM 1将验证 使用验证性因素分析；以及

PROJECT SUMMARY This 21-026”. low- stigma cancer cancer cervical cancer and Institute measure cervical Yale the this explanatory sexual facilitators in sexual randomly explore community members individual, stigma reduce at application is being submitted in response to the Notice of Special Interest (NOSI) identified as "NOT-CA- Cervical cancer is the most common cancer among women in the world, disproportionately affecting and middle-income ountries, where 85% of cervical cancer cases occur. Cancer stigma and sexual may be obstacles to successful cancer prevention, screening and treatment programs, undermining the care continuum, particularly with ervical cancer screening and treatment. The link between cervical and the human papilloma virus, a common sexually transmitted infection (STI), has further stigmatized cancer. I t is, therefore, necessary to understand the impact of cancer and sexual stigma on cervical screening and treatment uptake to develop interventions to educe stigma and strengthen screening treatment. The Yale Center for Methods in I mplementation and Prevention Science, in collaboration with f or Implementation Science and Health and Kathmandu University in Nepal, is conducting a study t o acceptability, feasibility, cost, and sustainability of, as well as to explore f acilitators and barriers to, cancer screening and treatment in central Nepal, supported by the parent grant to this supplement, Cancer Center's (YCC) P30 CA016359, “Yale Comprehensive Cancer Center Support Grant”, for which principal investigator of t his supplement application serves as Assistant Director, Global Oncology With research well underway to serve as a platform for the current study, we propose to implement an mixed-method approach to assess the i nfluence of cervical cancer stigma, and other intersecting stigmas on cervica l cancer screening uptake and partner disclosure, and explore the drivers and of such stigma. the cancer stigma scale and STI stigma and shame scale for use Nepal further, examine the prospective association of cancer and stigma with the uptake and disclosure to male partners of cervical cancer screening among 424 selected women of 30 to 60 years residing in the Dhulikhel municipality in central Nepal. Aim 2 will the drivers, facilitators and manifestations of cervical cancer stigma at individual, family, and level using qualitative in-depth interviews among purposively selected women (n=8), family (n=8) and community leaders (n=8) guided by the Health Stigma and Discrimination Framework at family, health provider and community level, aiming to identify promising components of a future reduction intervention. The study will provide insights into key factors for future programmatic efforts to stigma and improve access to cervical cancer screening and treatment in low resource settings, while, the same time, further strengthening the parent grant's Global Oncology Program. c c r . Aim 1 will validate using confirmatory factor analysis; and