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中文摘要
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项目总结 FaceBase III Hub的目标是创建一个数据存储库,为整个社区提供服务 牙科和颅面研究人员通过共享与颅面发育相关的不同数据 以及其他可以利用多样化数据的研究社区 在FaceBase存储库中。 FaceBase的设计遵循公平数据原则:数据是可找到的、可访问的、 可互操作、可重复使用。到目前为止,我们已经取得了巨大的成功,获得了新的研究 团队以遵守公平的方式向FaceBase提交数据。不过,从一开始, 在FaceBase III中,数字存储库社区开发了一套新的原则 旨在促进对存储库中包含的数据的信任,目标是促进 更广泛地重用存储库中的数据。透明的信任原则, 责任。以用户为中心、可持续发展和技术已被确定为 增加用户对数据存储库的信心,从而促进数据的使用和重用。 对FaceBase用户的调查和采访表明,FaceBase在 社区是一个高质量、值得信赖的储存库。然而,故意应用 信任指导方针的优势在于使FaceBase承诺遵守这些原则 更明确,提高我们在核心之外促进使用FaceBase数据的能力 颅面研究社区,更好地为NIH研究中的用户提供服务 社区。 在本提案中,我们寻求通过明确确定、定义和采用 FaceBase中的操作原则,以满足社区商定的信任标准(AIM 1)。信任的一个关键部分是定义特定的衡量标准,使人们能够评估 数据存储库。为此,我们将利用FaceBase提供的大量内置分析 收集以定义影响的关键绩效指标,并生成报告结构以 将这些指标传播给FaceBase用户社区(目标2)。 最终,我们的目标是使FaceBase Hub成为一个经过认证的可信数据存储库。 认证将在我们的用户社区中为FaceBase Hub建立更大的可信度 不太熟悉FaceBase的用户。从长远来看,采用信任原则将确保 存放在我们这里并委托给我们保管的数据集将保持在最高水平 质量的问题。
英文摘要
PROJECT SUMMARY The goal of the FaceBase III Hub is to create a data repository to serve the entire community of dental and craniofacial researchers by sharing diverse data related to craniofacial development and dysmorphia, as well as other research communities that can leverage the diverse data that is in the FaceBase repository. FaceBase was designed to follow FAIR data principles: that data be Findable, Accessible, Interoperable, and Reusable. To date, we have had significant success getting new research teams to submit data to FaceBase in a manner that adheres to FAIR. However, since the start of FaceBase III, the digital repository community has developed a new set of principles designed to promote trust in the data contained in a repository with the goal of promoting broader reuse of the data within the repository. The TRUST principles of Transparency, Responsibility. User Focus, Sustainability, and Technology have been identified as core to increasing users’ confidence in a data-repository and hence promoting data use and reuse. Surveys and interviews of FaceBase users indicate that FaceBase is perceived within the community as being a high-quality trustworthy repository. However, a deliberate application of TRUST guidelines has the advantage of making FaceBase commitment to these principles more explicit, increasing our ability to promote the use of FaceBase data outside of the core craniofacial research community, and better serving our users across the NIH research community. In this proposal, we seek to achieve these goals by explicitly identifying, defining, and adopting operational principles in FaceBase to meet community agreed-upon standards for TRUST (Aim 1). A critical part of TRUST is to define specific metrics that enable one to evaluate the impact of the data repository. To this end, we will leverage the extensive built-in analytics that FaceBase collects to define key performance metrics of impact and produce a reporting structure to disseminate those metrics to the FaceBase user community (Aim 2). Ultimately, the goal is for the FaceBase Hub to become a certified trusted data repository. Certification will establish greater credibility for the FaceBase Hub with our user community and with users less familiar with FaceBase. Long term, the adoption of TRUST principles will ensure that datasets deposited with us and entrusted to our care will be maintained at the highest level of quality.
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Center for TMD IMPACT
Hybrid- and Multi-Cloud Storage Strategies for Cost-effective Deployment of Data Resources
USC FaceBase III Craniofacial Development and Dysmorpholoy Data Management and Integration Hub
Mechanisms and rescue of craniosynostosis associated with gene-environment interaction
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