Training Program in Metabolic Biology

项目总结/摘要 在代谢生物学（TPMB）加州大学伯克利分校/加州大学旧金山分校联合培训计划提供了独特的机会， 学员在严格的，可重复的科学获得坚实的基础，并获得专业技能 和知识，以支持人类代谢健康和疾病研究领域的未来领导者。建造 围绕一个跨部门、跨机构的培训计划，它汇集了世界领先的研究人员， 以及UCB营养科学和毒理学系（NST）和UCSF糖尿病系的导师 中心（DC）为博士前研究员提供无与伦比的培训经验。港口及航运局致力吸引 来自不同学术背景的高素质学生，包括生物化学，细胞和 分子生物学、营养学和生理学。我们的课程是建立在奖学金的发展， 研究，教学和专业服务的技能，以建立早期研究的目标 独立性，并为研究诚信和责任奠定基础。除了服用TPMB 强调人类健康和代谢调节疾病主题的特定课程，研究设计 和再现性，数据分析和解释，以及道德行为，学生将能够旋转 通过UCB和UCSF Parnassus校园的实验室进行。TPMB学生将 体验一个培育，多样化和令人兴奋的环境，建立了一个完善的和综合的 社区的项目领导，研究人员和导师在两个校区，并充分意识到， 这一做法带来的机遇和潜在挑战。为了做出明智的选择， 轮换新生将接触到各种代谢为中心的研究计划 通过由所有TPMB教师提供的介绍性讲座，并参加该计划的联合年度务虚会 提供讲座，海报，并与教师，学生和博士后的社会互动。TPMB的核心优势 是我们师资队伍的素质和呼吸人体健康与新陈代谢的重点研究课题，范围广泛 从摄食行为的中枢调节到脂肪细胞生物学和脂肪细胞， 从单细胞测序到代谢组学、遗传学、干细胞生物学和生物工程学 以及在临床和临床前环境中进行研究的能力。这种广泛的专业知识和 方法促进合作科学，并准备TPMB学生成功过渡到 在学术界，工业界和政府的独立职业，以解决核心问题的使命 NIDDK并改善人类健康和福祉。

Project Summary/Abstract The UC Berkeley/UCSF joint Training Program in Metabolic Biology (TPMB) offers unique opportunities for trainees to gain a strong foundation in rigorous, reproducible science, and to acquire the professional skills and knowledge to support future leaders in the field of human metabolic health and disease research. Built around an inter-departmental, trans-institutional training program, it brings together world-leading researchers and mentors from UCB's Department of Nutritional Sciences and Toxicology (NST) and UCSF's Diabetes Center (DC) to offer an unparalleled training experience for predoctoral fellows. TPMB seeks to attract a diverse group of highly qualified students from various academic backgrounds including biochemistry, cell and molecular biology, nutrition, and physiology. Our curriculum is build around development of scholarship and skills in research, teaching and professional service with the goals of establishing early research independence and laying a foundation for research integrity and responsibility. In addition to taking TPMB specific courses that emphasize human health and disease topics in metabolic regulation, research design and reproducibility, data analysis and interpretation, as well as ethical conduct, students will be able to rotate through laboratories both on the UCB and UCSF Parnassus campuses in their first year. TPMB students will experience a nurturing, diverse, and exciting environment that has build a well-established and integrated community of program leadership, researchers and preceptors across the two campuses and is well aware of the opportunities and potential challenges this approach offers. In order to make informed choices for their rotations incoming students will be exposed to the variety of metabolism centered research in the program through introductory lectures given by all TPMB faculty and participate in the programs joint annual retreat offering talks, posters, and social interactions with faculty, students, and postdocs. A central strength of TPMB is the quality of our faculty and the breath of human health and metabolism focused research topics ranging from central regulation of feeding behavior to adipocyte biology and ß-cells and state-of-the-art technical approaches from single-cell-sequencing, to metabolomics, genetics, stem cell biology, and bioengineering and the ability to pursue research in both clinical and preclinical settings. This wide range of expertise and approaches foster collaborative science and prepare TPMB students to successfully transition into independent careers in academia, industry, and government to tackle problems central to the mission of NIDDK and to improve human health and wellbeing.