Core D. Administration Core

核心D，摘要 该计划的首要目标是了解结核分枝杆菌生物学的关键途径- 这种病原体在世界范围内杀死的人比任何其他病原体都多。它将侧重于复杂的途径， 重要的是适应疾病相关的压力，通过使用先进的遗传和生物化学方法， 合作者开发的。这项工作将由一个合作调查小组完成， 四个不同但相互关联的项目，并由四个核心支持。认真的项目管理至关重要 这个项目的成功行政核心将提供该项目管理， 最大限度地提高方案的效率和协同作用。具体而言，行政核心将 管理和协调该计划的项目和核心，包括资源和财务管理， 合同协议的管理，以及问题的识别和解决;促进沟通， 项目和核心之间的协同作用;以及管理和执行与外部合作伙伴的沟通。 !

Core D, Abstract The program’s overarching goal is to understand key pathways in the biology of Mycobacterium tuberculosis – the pathogen that kills more people than any other worldwide. It will focus on complex pathways that are important in adaptation to disease-relevant stressors, by using advanced genetic and biochemical methods that the collaborators have developed. The work will be done by a team of collaborative investigators, organized into four distinct but interrelated projects, and supported by four cores. Careful project management will be essential to the success of this program. The Administrative Core will provide this project management and is a key component to maximizing efficiency and synergies of the program. Specifically, the Administrative Core will manage and coordinate the projects and cores of the Program, including resource and fiscal management, management of contractual agreements, and problem identification and resolution; facilitate communication and synergy amongst the projects and cores; and manage and execute communications to external partners. !