Clinical Outcomes Research Training in Female Lower Urinary Tract Disorders

项目总结 女性下尿路疾病很常见，如尿失禁和尿路感染。 (每年影响数以百万计的妇女)，费用高昂，管理不佳。此外，不充分的研究是 在这一领域执行，防止开发新的和个性化的治疗方法和战略，以优化 关爱和幸福。这在一定程度上是因为很少有医生和科学家接受过严格研究这些问题的培训。 精神错乱。T32将通过培训医学临床研究员和博士后研究员来帮助满足这一需求 成为女性下尿路疾病临床结局研究领域的领导者。具体地说， 华盛顿大学医学院T32项目的目标是：1)建立严格的招聘 和遴选程序，以确定最有前途和最多样化的专注于研究的博士和博士研究员；2) 提供结构化而又灵活的环境，学员可在其中接受个性化指导和 女性下尿路疾病的综合训练、研究方法、道德操守 研究和拨款；3)提供财政支持和(受保护的)时间，使学员能够获得硕士学位 临床研究或人口健康科学学位，或临床结果相关课程 研究；4)继续并加强现有的强有力的会议和教学系列，在这些会议和教学系列中，学员讨论 女性泌尿系疾病的当前临床主题和相关研究方法；5) 实施强有力的职业和职业发展计划，以促进学员过渡到 初级教员地位；6)创建支持、响应和灵活的管理结构，以吸引和培养 最杰出的受训人员，特别是妇女和代表性不足的少数群体；以及7)不断评价 并根据学员的需求改进该计划。该计划将接受临床(医学博士、医学博士)和 由至少由以下成员组成的指导团队为博士后研究员提供长达三年的研究培训 一名临床研究人员和一名方法学(临床结果)研究员。至少有一位导师(初选)将 成为在他/她的领域有地位的高级研究员或临床医生，有资金支持，并有很好的指导 有过往记录。该计划结构旨在培养一种跨学科和协作的文化， 这些合作关系将带到未来的目标。为此，医学博士和博士实习生将 在每周的临床和研究会议以及职业和职业发展活动中团结一致。 研究员还可以选择进入硕士学位课程学习临床结果 研究方法，或通过特定的研究生水平课程来增强他们现有的技能。这一计划将 为下一代女性下尿路疾病的医学和博士研究人员做好准备 高质量的临床结果研究，带来了亟需的方法严谨性和协作性，跨 对这一领域最紧迫的问题采取纪律措施。

PROJECT SUMMARY Female lower urinary tract disorders, such as urinary incontinence and urinary tract infections, are common (affecting millions of women each year), costly, and sub-optimally managed. Additionally, insufficient research is performed in this area, preventing the development of new and personalized therapies and strategies to optimize care and well-being. This is, in part, because few physicians and scientists are trained to rigorously study these disorders. This T32 will help meet this need by training MD clinical fellows and PhD post-doctoral fellows to become leaders in the field of clinical outcomes research in female lower urinary tract disorders. Specifically, the aims of this Washington University School of Medicine T32 Program are to: 1) establish a rigorous recruitment and selection process to identify the most promising and diverse research-focused MD and PhD fellows; 2) provide a structured, yet flexible, environment in which trainees receive individualized mentoring and comprehensive training in female lower urinary tract disorders, research methods, the ethical conduct of research, and grant-writing; 3) provide financial support and (protected) time to allow trainees to obtain a Master’s degree in Clinical Investigation or Population Health Sciences, or relevant coursework in clinical outcomes research; 4) continue and augment a robust existing conference and didactic series in which trainees discuss current, clinical topics in female urinary tract disorders and research methods relevant to these disorders; 5) implement a robust professional and career development program tailored to enhance trainees’ transition to junior faculty status; 6) create a supportive, responsive, and flexible administrative structure to attract and nurture the most exceptional trainees, particularly women and under-represented minorities; and 7) continually evaluate and improve the Program in response to trainees’ needs. This Program will accept clinical (MD, MD/PhD) and post-doctoral PhD fellows for up to three years of research training by a mentoring team composed of at least one clinical and one methodologic (clinical outcomes) researcher. At least one of the mentors (the primary) will be a senior researcher or clinician who is established in his/her field, funded, and has an excellent mentorship track record. The Program structure is designed to foster a trans-disciplinary and collaborative culture, with the goal that these cooperative relationships will carry into the future. To that end, MD and PhD trainees will be united at weekly clinical and research conferences and in career and professional development activities. Fellows will also have the option of matriculating in a Master’s degree program to learn clinical outcomes research methods, or enhancing their existing skill set with specific graduate level courses. This program will prepare the next generation of MD and PhD researchers in female lower urinary tract disorders to perform high- quality clinical outcomes research, bringing much-needed methodologic rigor and a collaborative, trans- disciplinary approach to the most pressing questions in this field.