Pilot Projects Program

摘要 试点项目计划。路易斯维尔糖尿病与肥胖大学的首要使命 该中心的目的是加强和丰富心脏代谢健康和疾病潜在机制的研究。 根据这一使命，科布雷第三阶段试点项目方案将提供资金、技术和 为糖尿病、肥胖症和心血管生物学领域的试点项目提供智力支持。申请者： 该计划将主要来自路易斯维尔大学学术部门的初级教员 对开发心脏代谢性疾病的研究项目感兴趣。此外，功勋卓著 职业生涯中期和高级研究人员提交的项目，建议改变领域或指导他们的未来 针对心血管或代谢性疾病的研究将被考虑资助。试点项目赠款 申请将每年征集，并根据审查结果授予不超过两年的期限 以及内部赠款评估员和外部咨询委员会的建议。此外，我们还将 为每个获奖者提供一个强大的指导团队，以指导他们的项目的发展 需要联邦资金，并提供职业指导。该计划的具体目标是：(1) 支持创新的心脏代谢研究；(2)提供科学和专业的指导，以奖励 受助者；(3)加强糖尿病和肥胖中心的竞争力；(4)监测效率 和试点计划的有效性。我们将鼓励两者融合概率较高的项目 利用并提升当前中心的知识和能力。这种方法将有助于确保 我们增加了该中心的调查人员数量，并增强了我们进行基本和 翻译研究。

ABSTRACT PILOT PROJECT PROGRAM. The overarching mission of the University of Louisville Diabetes and Obesity Center is to enhance and enrich research into the mechanisms underlying cardiometabolic health and disease. In line with this mission, the Pilot Project Program of Phase III of the COBRE will provide financial, technical, and intellectual support to pilot projects in the areas of diabetes, obesity, and cardiovascular biology. Applicants for the Program will derive primarily from junior faculty within academic departments at the University of Louisville who have an interest in developing research programs in cardiometabolic disease. Additionally, meritorious projects submitted by mid-career and senior investigators proposing to change fields or direct their future research toward cardiovascular or metabolic disease will be considered for funding. Pilot project grant applications will be solicited annually and awarded for a period of not more than two years based on the review and recommendations of internal grant evaluators and the External Advisory Committee. In addition, we will provide each awardee with a strong mentorship team to chaperone the development of their projects to the level required for federal funding and to provide career guidance. The specific objectives of the program are to: (1) support innovative cardiometabolic research; (2) provide scientific and professional mentorship to award recipients; (3) strengthen the competitiveness of the Diabetes and Obesity Center; and (4) monitor efficiency and effectiveness of the pilot program. We will encourage projects that have a high probability of both integrating with and advancing the knowledge and capabilities of the current Center. This approach will help ensure that we increase the mass of investigators in the Center as well as augment our ability to conduct basic and translational research.