Enrichment Program

项目摘要-浓缩浓缩液 慢性肾脏疾病影响着3000多万美国人，使他们面临心血管疾病的主要风险。 最大的疾病，其他合并症和死亡，并利用约28%的年度医疗保健预算。这些令人震惊 统计数字突出表明，迫切需要确定新的、具有成本效益的治疗方法。的主要目标 乔治M.西北大学奥布莱恩肾脏研究核心中心（NU-GoKIDNEY）将促进 并支持研究发现新的治疗方法，这将改变预防和 治疗肾脏疾病，并最终导致治愈。拟议的浓缩方案是一项重要的 拟议NU-GoKIDNEY奥布莱恩中心的组成部分，旨在：告知中心研究者 相关研究的最新进展;通过培训增加肾脏疾病翻译人员 临床和基础科学方法的研究人员，以推进治疗发现研究， 吸引其他相关领域的研究人员参与肾脏研究;并促进跨学科研究 需要开展合作，制定创新解决方案，以克服开发治疗方法的障碍。 相应地，丰富计划将支持一些教育活动和研究场所 旨在汇集来自不同背景的教师和学员-临床和基础肾脏 研究人员、化学家、物理学家、药理学家和纳米医学专家。特定组件 丰富计划包括以下内容：1）一系列强大而全面的教学和 以课堂为基础的研讨会、课程和会议，重点介绍肾脏研究的最新进展，并 培训和支持新的研究人员在肾脏治疗的发展。2)一系列跨学科的事件 包括研讨会和科学果酱，涉及奥布莱恩中心基础科学和临床教师及其 实习生3)一年一度的奥布莱恩中心研讨会集中在确定治疗目标的所有阶段， 的发现4)一个科学高推广计划，以确定和指导高度积极的学生从 在科学和肾脏研究方面处于不利地位。5)一系列的咖啡馆科学专注于 关于肾脏疾病研究和治疗的进展，在一个创新和互动的论坛上发表， 将包括中心调查人员和普通公众。强化计划的另一个目标是提供 为研究人员和其他NIDDK资助的奥布莱恩成员提供了宝贵的基于网络的学习资源， 肾脏中心通过我们的肾枢纽网站。

PROJECT SUMMARY – ENRICHMENT PROGRAM Chronic kidney diseases affect more than 30 million Americans, placing them at major risk for cardiovascu- lar disease, other comorbidities and death and utilize ~ 28% of the annual medicare budget. These alarming statistics underscore the urgent need to identify new, cost-effective treatments. The major objective of the George M. O'Brien Kidney Research Core Center at Northwestern University (NU-GoKIDNEY) is to promote and support research into the Discovery of Novel Therapeutics that will transform the prevention and treatment of kidney diseases and eventually lead to cures. The proposed Enrichment Program is an essential component of the proposed NU-GoKIDNEY O'Brien Center and is designed to: inform Center investigators of the latest advances in relevant research; grow the kidney disease translational workforce by training investigators in clinical and basic science approaches to advance therapeutic discovery research and by attracting investigators from other, relevant fields into kidney research; and catalyze inter-disciplinary collaborations needed to develop innovative solutions to overcome barriers to developing treatments. Accordingly, the Enrichment program will support a number of educational events and research venues designed to bring together faculty and trainees from diverse backgrounds – clinical and basic kidney investigators, chemists, physical scientists, pharmacologists and nanomedicine experts. Specific components of the Enrichment program include the following: 1) A series of robust and comprehensive didactic and classroom-based seminars, courses and meetings to highlight the latest advances in kidney research and to train and support new investigators in kidney therapy development. 2) A series of cross-disciplinary events including Workshops and Science-Jams, involving O'Brien Center basic science and clinical faculty and their trainees. 3) An annual O'Brien Center symposium focused on identifying therapeutic targets at all stages of discovery. 4) A Sci-High outreach program to identify and mentor highly motivated students from disadvantaged backgrounds in science and kidney investigation. 5) A series of Cafés Scientifiques focused on advances in kidney disease research and treatments, delivered in an innovative and interactive forum that will include Center investigators and the lay public. An additional goal of the Enrichment program is to provide valuable web-based learning resources for investigators and members of other NIDDK-funded O'Brien and Kidney Centers through our nephro-HUB web site.