CORE A - Administrative Core

摘要 核心A是负责支持研究目标的全面管理的行政核心设施 和方案目标，并进一步负责满足所有方案管理要求 在涉及的多个机构中。核心A将提供完成以下任务所必需的服务 针对整个计划的中心假设的研究目标：蛋白质糖基化和糖蛋白 重塑改变了脓毒症的凝血障碍和炎症。核心A提供以下管理功能 所有项目、核心设施和计划资助人员都需要。核心A将成为 项目参与者之间的程序性沟通，包括项目负责人、核心负责人、咨询 董事会成员、合作者和顾问，以及实验室和研究人员。整体而言 核心A的行政目标是在#年建立和维持基本的方案行政职能 尽可能以最高效和最优化的方式。此外，核心A将继续建立和维护 根据需要与多个办公室和工作人员进行有效的部门间和机构间沟通 完成所需的行政职责。核心A行政设施将保存相关记录 满足申请中详细说明的管理要求的计划活动。行政部门 核心A的职能包括通过多种日常模式维护有效的办公基础设施 通信、监测项目和核心支出，协助指导和管理 方案人员、相关方案会议和进度报告的执行和记录保存， 编制和维护项目人员通信列表，协助项目人员 关于方案出版物和撰写、提交方案报告、组织会议 项目调查员、工作人员和顾问委员会成员，以及项目的组织和执行 人员非现场旅行，包括年度计划务虚会。核心A将进一步协助 项目人员作为圣巴巴拉平房医院医生和研究办公室工作人员的联络人 促进通信和文件传输，从而能够对人类受试者使用 支持该计划的内部审查委员会认证。核心A的结构和组织 包括一名核心领导和计划助理，他们将共同提供 支持计划项目和核心人员及活动。

SUMMARY Core A is the administrative core facility responsible for overall administration in support of the research aims and goals of the program, and is further responsible for meeting all programmatic administrative requirements of the multiple institutions involved. Core A will provide services that are essential for the completion of research goals addressing the central hypothesis of the overall program: Protein glycosylation and glycoprotein remodeling alter the coagulopathy and inflammation of sepsis. Core A provides administrative functions that are needed by all of the projects, core facilities, and program-funded personnel. Core A will be the nexus of programmatic communications among program participants including project leaders, core leaders, advisory board members, collaborators and consultants, and laboratory and research personnel. The overall administrative goal of Core A is to establish and maintain essential programmatic administrative functions in the most efficient and optimal manner possible. In addition, Core A will continue to establish and maintain effective inter-departmental and inter-institutional communications with multiple offices and staff as needed to achieve the administrative duties required. The Core A administrative facility will maintain records of relevant program activities in fulfilling the administrative requirements as detailed in the application. The administrative functions of Core A include maintaining an effective office infrastructure with multiple routine modes of communication, monitoring project and core expenditures, assistance with orientation and administration of program personnel, execution and record keeping of relevant programmatic meetings and progress reports, composing and maintaining program personnel communication lists, assistance to program personnel regarding program publications and compositionand submission of program reporting, organization of meetings of program investigators, staff, and advisory board members, and organization and execution of program personnel off-site travel including annual program retreats. Core A will further operate in assistance with project personnel as a liaison with Santa Barbara Cottage Hospital physicians and research office staff in facilitating communications and documents transfers enabling accreditation regarding human subjects use with Internal Review Board certification in support of the program. The structure and organization of Core A includes a Core Leader and Program Assistant whom together will provide the administrative functions in support of program project and core personnel and activities.