UCLA Short-Term Research Experience to Unlock Potential (UCLA STEP-UP)

项目摘要/摘要 加州大学洛杉矶分校建议作为西部地区协调中心 对于NIH-NIDDK NIDDK短期体验计划，以释放潜力(升级式)计划。这个 UCLA Step Up将为来自加州大学洛杉矶分校的有前途的高中生提供丰富的暑期研究经验 代表性不足的种族/少数民族群体以及来自其他群体的学生代表性不足 (URG)在医学和科学方面。加州大学洛杉矶分校的首要目标是为参与做准备。 生物医学和临床健康科学研究领域的学生。 URM和URG社区在科研队伍中的参与不足是一个关键问题 这些限制影响了卫生研究的未来，最终影响了我们国家的健康。获得高质量的 研究生涯所需的生物医学科学教育在很大程度上仍然受到以下因素的影响 社会经济阶层、种族/族裔、性别和/或民族血统。迫切需要激励和装备 具备批判性理解、探索和参与所需技能的高中生 科学研究，以及发展科学研究所需的信心和沟通技能 事业。对高中教育时间表的早期干预可以帮助建立一个多样化和包容性的 科学工作者。该计划的主要组成部分包括：1)了解负责任的行为 研究，2)接触科学研究环境，3)发展与研究导师的关系，4) 基本统计，5)通用实验室设备的使用，6)研究摘要的制定，7)课程 健康差距，以及生物医学研究如何改善健康结果，大学规划，研究 演讲技巧，以及科学的职业探索。该计划的首要目标是增加 准备在NIDDK任务区从事职业生涯的URM和URG高中生人数 生物医学和临床健康科学。为此，具体目标如下： 具体目标1：每年让美国西部地区25名URM或URG高中生参加 在与疾病相关的基础研究、临床研究或转化性研究方面有指导的夏季科研经验 在NIDDK任务中。 具体目标2：每年为25名URM或URG高中生提供课程结束 有机会根据他们的暑期研究项目提交书面报告和PowerPoint演示文稿 一年一度的NIDDK升级研究研讨会在马里兰州贝塞斯达的NIH校区举行。 具体目标3：评估加州大学洛杉矶分校加强准备25所URM或URG高中的有效性 学生每年进行生物医学研究，与研究导师接触，制作出科学的 演讲，增强他们追求并成功毕业于STEM本科专业的愿望，以及 在科学相关领域攻读研究生课程，重点是NIDDK任务区。

PROJECT SUMMARY/ABSTRACT The University of California, Los Angeles proposes to serve as a Coordinating Center for the Western Region for the NIH-NIDDK NIDDK Short-Term Experience Program to Unlock Potential (STEP-UP) Program. The UCLA STEP-UP will provide an enriched summer research experience for promising high school students from underrepresented racial/ethnic minority (URM) groups as well as students from other groups underrepresented (URG) in medicine and science. The overarching goal of the UCLA STEP-UP is to prepare participating students for research careers in the biomedical and clinical health sciences. The paucity of participation from URM and URG communities in the scientific research workforce is a critical limitation affecting the future of health research, and ultimately our nation’s health. Access to a high-quality biomedical science education required for a research career remains largely influenced by factors such as socioeconomic class, race/ethnicity, gender and/or national origin. There is a critical need to motivate and equip URM and URG high school students with the requisite skill set to critically understand, explore and engage in scientific research, as well as the confidence and communication skill set required for advancement in scientific careers. Early interventions in the high school education timeline can help to build a diverse and inclusive scientific workforce. The Program’s main components include: 1) Understanding responsible conduct of research, 2) Exposure to scientific research environments, 3) Developing relationships with research mentors, 4) Basic statistics, 5) Use of common laboratory equipment, 6) Development of a research abstract, 7) Lessons in health disparities, and how biomedical research can improve health outcomes, 8) College planning, 9) Research presentation skills, and 10) Scientific career exploration. The Program’s overarching goal is to increase the number of URM and URG high school students prepared to pursue careers in NIDDK mission area related biomedical and clinical health sciences. To this end, the Specific Aims are as follows: Specific Aim 1: To engage 25 URM or URG high school students in the US Western Region each year in a mentored, summer scientific research experience in basic, clinical, or translational research related to conditions within the NIDDK mission. Specific Aim 2: To provide 25 URM or URG high school students each year with an end of program opportunity to present written reports and PowerPoint presentations based on their summer research projects at the annual NIDDK STEP-UP research symposium on the NIH campus in Bethesda, Maryland. Specific Aim 3: To evaluate the effectiveness of the UCLA STEP-UP to prepare 25 URM or URG high school students each year to conduct biomedical research, engage with research mentors, produce a scientific presentation, enhance their desire to pursue and successfully graduate with a STEM undergraduate major, and pursue graduate programs in a science-related field focusing on NIDDK mission areas.