Shared Resource Management

项目摘要/摘要-共享资源管理 CCSG支持的八个共享资源（SR）提供了经济高效的技术和服务访问， 联合国儿童基金会成员。制定工作人员代表是为了补充其他核心，但不与其他核心重叠，也不与其他核心共享 资源在UNM。它们由癌症中心研究管理局（CCRA）集中管理， Scott Ness博士(CMO)，共享资源副主任。所有的SR都有一个教员主任， 接受CCSG的工资支持，并参加与高级领导人的定期会议， 项目负责人。五个工作人员代表向用户收取费用（分析和转化基因组学、动物模型和 成像、流式细胞术、荧光显微镜和细胞成像、人体组织库和组织 分析），并利用集中式计费系统跟踪使用情况。三个（生物信息学，生物统计学， 行为测量与人口科学）采用协作模式，跟踪教师的使用情况 或通过赠款收回的员工努力。通过包括监督在内的多种机制收集用户反馈 委员会，研究计划会议和匿名调查，结果由Ness使用，高级研究员 领导层和员工代表主任改进和战略性发展员工代表。上一个供资期间 三个SR（动物模型和成像，生物信息学和流式细胞术）在 我们已经对这一反馈做出了回应，并在利用率和用户反馈方面显示出了巨大的改善。所述SRs 显示出需求和收取的用户费用持续增长，包括持续的总体增长 自2015年上一次CCSG更新以来，我们的业务增长了近3倍，自2010年第一次CCSG更新以来，我们的业务增长了近3倍。这种增长 反映了联合国儿童基金会的持续改进和重大投资，包括220万美元用于新的 仪器仪表和翻新成本，500，000美元的非CCSG成本分摊收益， 成员和265，610美元的SR重点试点赠款，产生了480万美元（直接成本）的校外赠款 经费持续改进的一个例子是行为测量和人口科学 共享资源，这是发展，但现在已晋升为一个完整的SR。在此更新申请， CCSG资金被要求支持一个新的开发转化科学共享资源，该资源将 促进UNMCCC研究人员的发现转化为临床试验，整合相关研究 与UNMCCC正在进行的临床试验，与其他SR接口，以促进临床之间的合作 和基础/翻译研究者，同时支持临床科学家的招聘和保留。在 在本供资期内，CCSG资金支持了工作人员代表23%的业务预算， 主要由联合国儿童基金会成员使用。在过去5年中，SR的总按存储容量使用计费（计费） 超过300万美元，SR支持了139项同行评审的NIH赠款（总资金4900万美元）和128项 来自所有三个研究方案的联合国儿童基金会现任和前任成员都使用了工作报告。

Project Summary/Abstract - Shared Resources Management Eight CCSG-supported Shared Resources (SRs) provide cost-effective access to technologies and services to UNMCCC members. The SRs have been developed to complement but not overlap with other cores or shared resources at UNM. They are managed centrally by the Cancer Center Research Administration (CCRA) and Scott Ness, Ph.D. (CMO), Associate Director for Shared Resources. All of the SRs have a faculty Director who receives salary support from the CCSG and who participate in regular meetings with Senior Leaders and Program Leaders. Five SRs charge user fees (Analytical & Translational Genomics, Animal Models & Imaging, Flow Cytometry, Fluorescence Microscopy & Cell Imaging, Human Tissue Repository & Tissue Analysis) and utilize a centralized billing system for tracking utilization. Three (Bioinformatics, Biostatistics, Behavioral Measurement & Population Science) operate with a collaborative model, tracking usage as faculty or staff effort recovered on grants. User feedback is collected through several mechanisms, including oversight committees, research program meetings and anonymous surveys, and the results are used by Ness, the senior leadership and the SR Directors to improve and strategically develop the SRs. During the previous funding period three SRs (Animal Models & Imaging, Bioinformatics and Flow Cytometry) were significantly reorganized in response to this feedback and have shown dramatic improvements in utilization and user feedback. The SRs have demonstrated consistent growth in demand and in user fees collected, including continued overall growth since the last CCSG renewal in 2015 and nearly 3-fold growth since our first CCSG renewal in 2010. This growth reflects continuous improvements and significant investments made by UNMCCC, including $2.2 million for new instrumentation and renovation costs, $500,000 in non-CCSG cost sharing benefits that reduce the charges for members and $265,610 in SR-focused pilot grants that generated $4.8 million (direct costs) in extramural grant funding. An example of continuous improvement is the Behavioral Measurement & Population Science Shared Resource, which was developing but has now been promoted to a full SR. In this renewal application, CCSG funds are requested to support a new developing Translational Science Shared Resource, which will facilitate the translation of discoveries from UNMCCC investigators to clinical trials, integrating correlative studies with ongoing clinical trials at UNMCCC, interfacing with the other SRs to promote collaborations among clinical and basic/translational investigators while supporting the recruitment and retention of clinician-scientists. In the current funding period, CCSG funds supported 23% of the operating budgets for the SRs, which were predominantly used by UNMCCC members. During the previous 5 year, total chargebacks (billing) for the SRs was over $3 million, the SRs supported 139 peer-reviewed NIH grants ($49 million in total funding) and 128 current and former UNMCCC members from all three Research Programs used the SRs.