The University of Kansas Cancer Center

总体：摘要 堪萨斯大学癌症中心（KUCC）是一个矩阵联盟癌症中心，包括： 堪萨斯大学医学中心（KUMC）、位于劳伦斯的堪萨斯大学（KU-L）以及通过联盟 协议，斯托尔斯医学研究所（Stowers）和儿童慈善机构（CM）堪萨斯城。在 2020年，KUCC的171名成员获得了970万美元的NCI资金，以及总计5700万美元的癌症相关资金。 资金，自上次CCSG提交以来增加了800万美元。由一位经验丰富的全国性 著名的领导团队，罗伊·A。医学博士詹森带领KUCC走上了一条强劲的上升轨道， 自2004年以来，得到了超过4.67亿美元的慈善支持。在过去四年中， 一直在扩大与整个KUCC集水区社区的伙伴关系，招募高 创新的医生-科学家，扩大临床研究和早期临床试验。我们还 一直在推进下一代科学家和医疗保健提供者的教育，并提高 KUCC研究人员在国家科学界的影响力。KUCC制定了五个目标，以确保 KUCC在与癌症的斗争中处于领先地位： 1.利用独特的区域资产将研究发现从实验室和诊所转化为 推动新的抗癌疗法的发展。 2.提供最佳环境，集中精准医疗、基础科学探究、药物 发现和发展，以及行为干预，以减少癌症的发病率，发病率， mortality. 3.领导和实施一项全面的战略，以教育当前和下一代的癌症 癌症研究、治疗、预防和控制的研究人员和临床医生。 4.与主要利益相关者、社区倡导者和区域领导人合作，开发、推广和促进 以研究为基础的癌症预防、诊断、治疗、控制和生存策略， 我们的国家影响，改善癌症的结果，并确保健康公平。 5.通过培养创新的伙伴关系和合作来推进团队科学。 为了实现这些目标，KUCC有三个研究项目：1）癌症生物学，2）癌症预防和 对照，和3）药物发现、递送和实验治疗。此外，KUCC还支持 临床试验办公室，七个已建立的共享资源-生物标本，生物统计学和信息学，临床 药理学，流式细胞术，铅开发和优化，营养，转基因和基因- 目标-和一个开发共享资源-显微镜和分析成像。

OVERALL: ABSTRACT The University of Kansas Cancer Center (KUCC) is a matrix consortium cancer center that includes: The University of Kansas Medical Center (KUMC), the University of Kansas in Lawrence (KU-L) and via consortium agreement, the Stowers Institute for Medical Research (Stowers) and Children’s Mercy (CM) Kansas City. In 2020, 171 members of KUCC accounted for $9.7M of NCI funding and a total of $57M in overall cancer-related funding, an increase of $8M since the last CCSG submission. Supported by an experienced, nationally recognized leadership team, Roy A. Jensen, MD, has led KUCC on a strong upward trajectory that has been catalyzed by over $467M philanthropic support since 2004. Over the last four years, substantial progress has been made broadening partnerships with communities throughout the KUCC catchment area, recruiting highly innovative physician-scientists, and expanding clinical research and early phase clinical trials. We have also been advancing education for the next generation of scientists and healthcare providers and heightening the influence of KUCC researchers in the national scientific community. KUCC has established five aims to ensure KUCC leads in the fight against cancer: 1. Leverage unique regional assets to transform research discoveries from the laboratory and the clinic to drive new anticancer therapeutic development. 2. Provide the optimal environment to focus the power of precision medicine, basic science inquiry, drug discovery and development, and behavioral interventions to decrease cancer incidence, morbidity, and mortality. 3. Lead and implement a comprehensive strategy to educate both the current and next generation of cancer researchers and clinicians in cancer research, treatment, prevention, and control. 4. Partner with key stakeholders, community advocates and regional leaders to develop, promote, and foster research-based cancer prevention, diagnosis, treatment, control, and survivorship strategies to enhance our national impact, improve cancer outcomes and ensure health equity. 5. Advance team science by fostering innovative partnerships and collaborations. To accomplish these aims KUCC has three research programs: 1) Cancer Biology, 2) Cancer Prevention and Control, and 3) Drug Discovery, Delivery and Experimental Therapeutics. In addition, KUCC supports the Clinical Trials Office, seven established shared resources – Biospecimen, Biostatistics and Informatics, Clinical Pharmacology, Flow Cytometry, Lead Development and Optimization, Nutrition, and Transgenic and Gene- Targeting – and one developing shared resource – Microscopy & Analytical Imaging.