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COVID-19 Sample Collection and Vaccine Studies

COVID-19 Sample Collection and Vaccine Studies
COVID-19 样本采集和疫苗研究
批准号：
10497765
负责人：
Julie E. Ledgerwood
金额：
$48.59万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/10497765
关键词：
AdultBiologicalBiological AssayCOVID-19COVID-19 vaccineDevelopmentDoseEvaluationHumanImmune responseImmunityImmunologyIndividualInvestigationMeasuresMissionModerna COVID-19 vaccinePhasePreventiveProtocols documentationResearchResearch SupportSARS-CoV-2 infectionSafetySamplingSeverity of illnessTherapeuticimmune functionimmunogenicityopen labelresearch studysafety studysample collectionvaccine candidatevaccine trial

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中文摘要
翻译
针对COVID-19的候选疫苗的评估和支持转化免疫学研究的样本收集支持了更广泛的VRC使命。 对于本项目，根据VRC 200方案进行样本采集，而根据DMID 20-0003方案进行试验用候选疫苗评价。 VRC 200：用于获得研究用人体生物样本的多中心标本采集方案 DMID 20-0003：2019-nCoV疫苗（mRNA-1273）在健康成人中的安全性和免疫原性的I期、开放标签、剂量范围研究
英文摘要
The evaluation of a vaccine candidate targeting COVID-19 and collection of samples to support translational immunology research support the broader VRC mission. For this project, sample collection was conducted under the VRC 200 protocol while the evaluation of an investigational vaccine candidate was conducted under the DMID 20-0003 protocol. VRC 200: A Multicenter Specimen Collection Protocol to Obtain Human Biological Samples for Research Studies DMID 20-0003: Phase I, Open-Label, Dose-Ranging Study of the Safety and Immunogenicity of 2019-nCoV Vaccine (mRNA-1273) in Healthy Adults
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