Obesity: Biological, socioCultural, and environmental risk Trajectories (OBCT)

在欧洲，肥胖对社会经济地位(SEP)较低的人和社区的影响不成比例。有效的预防方法需要考虑(特定于SEP的)生物、社会文化和环境肥胖风险因素之间复杂和动态的相互作用。OBCT为卫生专业人员、研究人员、政策制定者和公众提供知识、地图和工具，以支持肥胖的可持续预防，特别是在低SEP社区。为了实现这一目标，我们量化了肥胖风险的生物、社会文化和固有环境风险因素的贡献，以及在不同生命阶段中和跨不同生命阶段的相互作用，并将由此产生的知识转化为实际有效的行动工具。具体来说，OBCT将：1)促进当前对肥胖风险和预测因素的理解，以及SEP在整个生命过程中的作用；2)确定特定肥胖相关行为的重要性，以防止关键人生阶段的肥胖；3)开发供广大公众和卫生专业人员使用的全面肥胖风险筛查；4)提供针对具体国家的肥胖趋势估计；5)提供关于环境肥胖性的数字地图集；6)描述与肥胖相关的心脏代谢风险的性别、年龄和SEP特征；7)制定量身定制的生活方式建议；8)确定肥胖相关政策对不平等的影响；9)为政策制定者提供决策支持仪表盘；10)提供共同开发的工具箱，以支持在低SEP社区实施政策建议。OBCT的结果突出了肥胖在哪里以及哪些领域是目标，并使研究社区、政策制定者、健康专业人员和公民能够调整和实施降低肥胖风险的政策，从而帮助整个欧洲预防肥胖--特别是在低SEP社区。

Obesity in Europe disproportionately affects people and communities with a lower socioeconomic position (SEP). Effective preventive approaches require consideration of the complex and dynamic interplay between (SEP-specific) biological, sociocultural and environmental risk factors of obesity across the life course. OBCT provides health professionals, researchers, policy makers and the public with knowledge, maps and toolsto supportsustainable prevention of obesity, with a particular focus on low SEP communities. To achieve this, we quantify the contribution of biological, sociocultural and built environmental risk factors of obesity risks and the interactions in and across various life stages, and translate the resulting knowledge into practical and effective tools for action. Specifically, OBCT will: 1) Advance the current understanding of obesity risks and predictors, and the role of SEP across the life-course; 2) Determine the importance of specific obesity-related behaviours to prevent obesity at key life stage transitions; 3) Develop a holistic obesity risk screener for use by the public at large and by health professionals; 4) Provide country-specific estimates of trends obesity; 5) Provide a digital atlas on the obesogenicity of environments; 6) Characterise obesity-related cardiometabolic risk profiles over gender, age and SEP; 7) Develop tailored lifestyle recommendations; 8) Determine the impact of obesity-related policies on inequality; 9) Provide a decision support dashboard for policy makers; 10) Provide co-developed toolboxes to support implementation of policy recommendations in low-SEP communities. OBCT’s outputs highlight where and in which domains obesity is to be targeted, and empower the research community, policymakers, health professionals and citizens to adapt and implement policies to reduce obesity risk, thereby helping to prevent obesity -particularly in low SEP communities - throughout Europe.