United States-Mali Research Ethics Training Program (US-Mali RETP)

项目摘要/摘要 在过去的四十年里，见证了公共卫生和临床研究的显著增长 在马里进行，部分原因是不断增加的国际研究合作和最近的埃博拉疫情 流行病。人类研究的这种增加，产生了对改善生物伦理领导、培训、 政策和研究。因此，确保研究人员和机构成员 马里的审查委员会(IRB)拥有必要的知识和能力，以确保研究符合道德标准， 文化和监管方面的预期。为了满足马里的伦理培训需求，我们提出了一种研究伦理 加强马里研究伦理教育和研究的能力建设计划，通过创新的 可持续能力发展模式，为下一代伦理研究人员做准备。本节目 将基于两个机构之间的密切合作-乔治华盛顿大学米尔肯研究所 美国公共卫生学院和巴马科科技大学 (USTTB)，马里。美国-马里研究伦理培训计划的总体目标(美国-马里 RETP)是为了加强马里的研究伦理教育和研究。我们的模式将专注于使用美国和 以非洲为基础的专业知识，以加强USTTB开发和领导新的硕士专业的能力 在研究伦理方面，并通过以下具体目标促进科技大学的可持续生物伦理事业； 具体目标1：加强USTTB主要教员的教学和课程优势，以提供 在马里研究伦理课程和指导。我们将实施教师发展计划，以 选定的马里教员旨在加强道德研究和培训方面的分析能力。选定的 马里教员将参加美国的强化课程，与GWSPH教员合作制定课程和 在二年级期间共同教授伦理学课程。具体目标2：发展研究伦理学专业 在现有的USTTB公共卫生硕士(MPH)计划内，培训一批核心的 马里在研究伦理方面有专长的专业人员。我们将开发一门新的研究伦理学课程 在USTTB的公共卫生项目中。道德模块也将作为一年制大专课程的一部分提供。我们 还将在USTTB举办短期培训讲习班和网络研讨会，包括基本和高级主题 每年。具体目标3：围绕马里研究伦理的关键优先事项促进研究。我们会 通过我们的学员进行相关的国家道德研究，以告知公共卫生、培训优先事项和 医疗保健的提供，包括传染病和新发疾病研究的伦理以及遗传学和 基因组学。具体目标4：在马里的USTTB内设立一个专门的“研究伦理股”。我们会 努力在USTTB内建立一个学术研究单位，负责协调生物伦理研究和 在贸易和技术合作委员会的活动，并加强我们的努力的可持续性。该股还将协调一个国家论坛，以 与马里卫生部(MoH)合作，讨论马里的研究伦理。

Project Summary/Abstract The past four decades, have witnessed a significant increase in public health and clinical research being conducted in Mali, driven partly by increasing international research collaborations and the recent Ebola epidemic. This increase in human research, creates an urgent need for improved bioethics leadership, training, policy and research. It is, therefore, critical and timely to ensure that researchers and members of institutional review board (IRB) in Mali have the requisite knowledge, and capacity to ensure the research meets ethical, cultural, and regulatory expectations. To meet the ethics training needs of Mali, we propose a research ethics capacity building program to strengthen research ethics education and research in Mali through an innovative model of sustainable capacity development to prepare the next generation of ethics researchers. This program will be based on close collaboration between two institutions – the George Washington University Milken Institute School of Public Health (GWU), USA and University of Science, Techniques & Technologies of Bamako (USTTB), Mali. The overall goal of the United States-Mali Research Ethics Training Program (US-Mali RETP) is to strengthen research ethics education and research in Mali. Our model will focus on using US and Africa-based expertise to strengthen USTTB’s capacity to develop and lead a new Master’s degree specialization in research ethics and promote a sustainable bioethics enterprise at USTTB through the following specific aims; Specific Aim 1: To enhance the pedagogical and curricular strengths of key USTTB faculty to deliver research ethics courses and mentoring in Mali. We will implement a faculty development program for selected Malian faculty aimed at enhancing analytical capacity in ethics research and training. The selected Malian faculty will participate in intensive courses in US, work with GWSPH faculty in developing curricula and co-delivery of ethics curriculum during year 2. Specific Aim 2: To develop a research ethics specialization within the existing USTTB Masters of Public Health (MPH) program in order to train a core group of professionals with expertise in research ethics in Mali. We will develop a new curriculum in research ethics within the MPH program at USTTB. The Ethics modules will also be offered as part of a one year Diplome. We will also offer short term training workshops and webinars at USTTB including both basic and advanced topics each year. Specific Aim 3: To promote research around key priorities for research ethics in Mali. We will through our trainees conduct relevant national research on ethics to inform public health, training priorities and health care delivery including ethics of research on infectious and emerging diseases as well as genetics and genomics. Specific Aim 4: To create a dedicated “Research Ethics Unit” within USTTB in Mali. We will work to establish an academic Research Unit within USTTB which will coordinate Bioethics research and activities at USTTB and enhance sustainability of our efforts. This unit will also coordinate a national forum to discuss research ethics in Mali in collaboration with the Ministry of Health (MoH) in Mali.