mDOT Administrative Core

主要调查者：库马尔，桑托什 MDOT-管理核心 摘要： 发现、优化和翻译时间精确干预的移动健康中心(MDOT 中心)将实现一种新的时间精准医学范例，以维持健康和管理不断增长的 慢性病的负担。MDOT中心将开发和传播方法、工具和 为研究人员发现、优化和翻译临时- 精确的移动健康干预。这种干预，当动态地个性化到每一时刻时 每个人的生物-心理-社会-环境背景，将在 医疗保健，使患者能够开始并维持直接 管理、治疗，在某些情况下甚至阻止医疗条件的发展。有条理的 围绕着三个技术研发项目，MDOT代表着一个独特的国家 将开发多种技术创新并支持将其转化为研究和 MHealth社区以可轻松部署的可穿戴设备、可穿戴设备应用程序和 智能手机，以及与之配套的mHealth云系统，都是开源的。 鉴于移动健康研究固有的跨学科、基于团队的性质，需要科学家跨越 MHealth中职能资源中心的学科和机构界限、管理和运作 技术需要一种协作文化，采用团队科学的方法，但在地理上是分散的 在虚拟环境中运行。MDOT将利用其成熟和非常成功的基础设施，自适应 程序敏锐，广为人知的传播平台，以及经验丰富的团队开发 与国家资源中心运营有关的行政和业务政策和程序。这个 管理核心不仅希望加强对协作项目(CP)和服务的研究 项目(SP)，但也要简化与很少或根本没有项目的新研究小组的沟通和参与 技术专长。为实现其目标，MDOT将开展以下活动。首先，MDOT将利用 建立组织结构和管理实践，以促进协调、沟通和 团队、CPS、SP和更大的研究社区之间的协作。其次，MDOT将建立 允许与CPS和SP成功合作的操作程序--这包括以下机制 接受、审查和批准资源的使用，并制定标准以确定其他合格人员的优先选择 CP/SP候选人。第三，MDOT将招募知名学者和全国公认的思想领袖来服务 在一个多元化的外部咨询委员会(EAC)上，负责就MDOT提供反馈和指导 研究议程。第四，MDOT将确保并利用制度支持，以适应和建立 成功实现调查小组提出的研究目标的中心。最后， Administration Core将制定可衡量的指标，以监控、评估和评估 MDOT技术，同时采取适应反馈和响应的客户服务方法 整个移动健康研究社区。 1

Principal Investigator: Kumar, Santosh mDOT – Administration Core Abstract: The mHealth Center for Discovery, Optimization & Translation of Temporally-Precise Interventions (the mDOT Center) will enable a new paradigm of temporally-precise medicine to maintain health and manage the growing burden of chronic diseases. The mDOT Center will develop and disseminate the methods, tools, and infrastructure necessary for researchers to pursue the discovery, optimization and translation of temporally- precise mHealth interventions. Such interventions, when dynamically personalized to the moment-to-moment biopsychosocial-environmental context of each individual, will precipitate a much-needed transformation in healthcare by enabling patients to initiate and sustain the healthy lifestyle choices necessary for directly managing, treating, and in some cases even preventing the development of medical conditions. Organized around three Technology Research & Development (TR&D) projects, mDOT represents a unique national resource that will develop multiple technological innovations and support their translation into research and practice by the mHealth community in the form of easily deployable wearables, apps for wearables and smartphones, and a companion mHealth cloud system, all open-source. Given that the inherently transdisciplinary, team-based nature of mHealth research requires scientists to cross disciplinary and institutional boundaries, administration and operation of a functional resource center in mHealth technologies requires a collaborative culture, with a team-science approach, that is geographically dispersed yet functional in a virtual setting. mDOT will utilize its established and highly successful infrastructure, adaptive procedural acumen, widely visible dissemination platforms, and deeply-experienced team to develop administrative and operational policies and procedures relevant to the running of a national resource center. The Administration Core will look to not only enhance the research of the collaborative projects (CPs) and service projects (SPs), but also to streamline communication and involvement with new research groups with little or no technological expertise. To achieve its goals, mDOT will pursue the following activities. First, mDOT will leverage an established organizing structure and managerial practice to facilitate coordination, communication, and collaboration among the team, CPs, SPs, and greater research community. Secondly, mDOT will establish operational procedures that allows for successful work with the CPs and SPs – this includes mechanisms to receive, vet, and approve the use of resources and devising criteria to prioritize the selection of other qualified CP/SP candidates. Third, mDOT will recruit eminent scholars and nationally recognized thought leaders to serve on a diverse external advisory committee (EAC) tasked with providing feedback and guidance on the mDOT research agenda. Fourth, mDOT will secure and leverage institutional support that accommodates and sets up the Center for success in achieving the research goals put forth by the investigating team. Finally, the Administration Core will develop measurable metrics to monitor, assess, and evaluate the quality and utility of mDOT technologies while taking a customer service approach that is adaptive to feedback and responsive to the mHealth research community at large. 1