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Accelerating paediatric formulation development through smart design and predictive science

Accelerating paediatric formulation development through smart design and predictive science
通过智能设计和预测科学加速儿科制剂开发
批准号:
101709
负责人:
金额:
$83.66万
依托单位:
依托单位国家:
英国
项目类别:
Collaborative R&D
财政年份:
2014
资助国家:
英国
项目状态:
已结题
起止时间:
2014 至 --

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中文摘要
翻译
该项目是英国大型制药公司、学术界和技术供应商之间的合作,旨在产生一种结构化的方法,以设计适合儿童年龄的药物,以及预测其质量和表现的技术。儿科药物目前是制药业内的一个“热门话题”,目前正在努力为儿童开发这种药物,这些药物在味道上是可以接受的,但也提供了这类患者所需的相关剂量和暴露。这一成果将为开发儿童药物提供一条更智能的途径,通过确定推动配方设计的最适当的测试战略来减少成本和开发时间。
英文摘要
This project is a collaboration between large UK pharmaceutical companies, academia and technology suppliers to generate a structured approach to designing age-appropriate medicines for children and technology for predicting their quality and performance. Paediatric medicine is currently a "hot-topic" within the pharmaceutical industry and there is a lot of effort going into developing such medicines for children that are acceptable in terms of taste but also provide the relevant dose and exposure required for such patients. The output will provide a smarter route to developing children’s medicines to reduce costs and time of development by determination of the most appropriate testing strategies that drive formulation design.
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