Cardiology and Pulmonary Clinical Research Training Program

项目总结 生物统计、流行病学和信息学(DBEI)与医学系、急诊科、儿科、麻醉学和重症监护医学系合作，建议继续并加强为成人和儿科心脏病和肺部临床研究的临床医生提供的创新、严格和成功的两到三年研究培训计划。要求每年提供6个博士后职位。 该培训计划侧重于在经验丰富的研究员的指导下进行研究，包括教学培训以及心脏病学或肺部临床研究的独立研究项目的规划、设计、实施、分析和解释，所有这些都旨在成为受训者学术生涯的下一步，为他/她作为独立资助的研究人员的职业生涯做准备。学员攻读临床流行病学理学硕士(MSCE)课程。授课课程包括流行病学和生物统计学的必修课、高质量临床研究的基础科学、心肺科学的方法论，包括心肺流行病学、高级流行病学、方案制定、复杂的生物统计学以及与受训者方法学兴趣相关的选修课。该培训计划通过由参与的教师举办的期刊俱乐部和临床研究会议、负责任的研究行为指导和一系列专业发展来加强。 该计划的目标是：1)培训临床医生成为严格和独立的学术调查人员，能够使用流行病学的一系列方法来解决心血管和肺部疾病的研究问题；2)提供与临床流行病学和心血管和肺部医学的教席密切指导的研究经验；以及3)加强流行病学和心血管和肺部医学之间的联系。 拟议计划的优势是：1)使用DBEI提供的结构在成人和儿科心脏病学和肺科成功开展研究培训计划的悠久而持续的历史，包括本培训计划；2)对心血管和肺部疾病临床研究感兴趣的教职员工之间建立的合作联系；3)向学员提供全面的课程和研究计划；以及4)具有成功培训记录的广泛的经验丰富的多学科教员导师。DBEI的广泛培训计划也为协作学习和成长提供了理想的环境。最后，宾夕法尼亚大学和佩雷尔曼医学院促进了一种学术环境，在这种环境中，基础、临床和转化性研究受到鼓励，并被视为对医生有吸引力的职业道路。

PROJECT SUMMARY The Department of Biostatistics, Epidemiology, and Informatics (DBEI) in collaboration with the Departments of Medicine, Emergency Medicine, Pediatrics, and Anesthesiology and Critical Care Medicine propose to continue and enhance an innovative, rigorous, and successful two- to three-year research training program for clinicians in both adult and pediatric cardiology and pulmonary clinical research. Six postdoctoral positions per year are requested. The training program focuses on mentored research with an experienced investigator that involves didactic training and the planning, design, conduct, analysis, and interpretation of an independent research project in cardiology or pulmonary clinical research, all intended to be the next step in a trainee's academic career preparing him/her for a career as an independently funded researcher. Trainees matriculate in the Master of Science in Clinical Epidemiology (MSCE) program. Didactic coursework consists of required courses in epidemiology and biostatistics, the basic sciences of high quality clinical research, methodology in cardiopulmonary science, including courses in cardiopulmonary epidemiology, advanced epidemiology, protocol development, sophisticated biostatistics, and elective courses relevant to the trainees' methodologic interests. The training program is enhanced by journal clubs and clinical research conferences conducted by participating faculty; instruction in the responsible conduct of research; and a professional development series. The objectives of the program are to: 1) train clinicians to be rigorous and independent academic investigators able to use the range of approaches available in epidemiology to address research issues in cardiovascular and pulmonary diseases; 2) provide closely mentored research experiences with faculty preceptors in clinical epidemiology and cardiovascular and pulmonary medicine; and 3) strengthen the links between epidemiology and cardiovascular and pulmonary medicine. Strengths of the proposed program are: 1) the long and continued history of successful research training programs in the adult and pediatric cardiology and pulmonary divisions using the structure provided by the DBEI, including this training program; 2) the collaborative links that have been forged among faculty with interests in clinical research in cardiovascular and pulmonary diseases; 3) the comprehensive course offerings and research programs that are available to trainees; and 4) an extensive set of experienced and multidisciplinary faculty mentors with successful training records. The broad training program in the DBEI also provides an ideal environment for collaborative learning and growth. Finally, The University of Pennsylvania and the Perelman School of Medicine promote an academic environment in which basic, clinical, and translational research are encouraged and viewed as attractive career paths for physicians.