Technology Core

项目摘要-技术核心 病毒系统生物学中心(CViSB)需要生成大型、多变量的数据集， 其中有必要修改现有的实验和计算方法或创造新的 方法：研究方法。技术核心的主要责任是提供最先进的、高吞吐量 组学和功能服务，以支持CViSB的项目。我们将利用我们丰富的专业知识 以及这些技术的经验，以确保我们保持作为尖端技术的地位 作为实验设施，我们将确定、开发和调整具有以下潜力的新兴技术 更进一步的CViSB科学fic目标。然后，我们将把这些创新的实验方法转化为 适用于分发和重用的标准化协议和方法。要实现这些目标 为了支持CViSB的总体目标和使命，我们有以下四个目标：(1)评估， 发展和完善寄主适应性多组学分析的实验方法和分析工具 免疫功能；(2)开发和改进具有成本效益的下一代大规模病毒方法 测序；(3)提供尖端的测序和组学服务，支持数据生成 CViSB项目和调查人员的需求；以及(4)创建和分发开放获取标准操作 程序、协议和方法。

Project Summary - Technology Core The Center for Viral Systems Biology (CViSB) requires the generation of large, multivariate datasets, many of which necessitate modifying existing experimental and computational approaches or creating novel methods. The Technology Core’s primary responsibility is providing state-of-the-art, high throughput omics and functional services to support CViSB’s Projects. We will leverage our considerable expertise and experience with these techniques and, to ensure that we maintain our position as a cutting-edge experimental facility, we will identify, develop and adapt emerging technologies with the potential to further CViSBs scientific aims. We will then translate these innovative experimental approaches into standardized protocols and methods that are suitable for distribution and reuse. To accomplish these objectives and support the overall mission of CViSB, we have the following four aims: (1) Evaluate, develop, and improve experimental methods and analysis tools for multi-omics analysis of host adaptive immune function; (2) Develop and improve cost-effective next-generation methods for large-scale virus sequencing; (3) Provide cutting-edge sequencing and omics services to support the data generation needs of CViSB’s Projects and investigators; and (4) Create and distribute open access standard operating procedures, protocols, and methods.