Students Training in Advanced Research

项目概要/摘要。 这是一个非常成功的加州大学戴维斯分校T35星星（学生培训， 高级研究）。在过去的20年里，该计划培训了225名DVM学生。学生 鼓励和指导提交假设驱动的研究建议，在他们的第一，第二， 偶尔会在专业课程的第三年。星星计划的目标是提供DVM 申请获得审查委员会批准的学生可获得助学金，参加有经验的培训 教师及其富有成效的研究团队在10周的结构化研究指导和 亲身实践的现代生物医学研究该计划强调5个基本研究目标：1）如何 获得知识和理解的一个人的科学领域; 2）如何制定一个科学的 合理和可检验的假设; 3）确定具体目标，进行有控制的有条理的 实验，并开发技术专长; 4）分析结果，得出结论，提出额外的建议 实验，并预测新的方向;和5）传达研究成果简洁和令人信服的， 他人负责任地进行研究和科学严谨是培训计划的关键组成部分。星星 该计划每年持续收到55至63名申请人，2015年扩大到15个职位 由NIH T35机制支持，以满足有兴趣参与的学生日益增长的需求， NIH相关研究。兴趣广泛的学生，从分子和细胞医学， 生物医学工程，病媒传播疾病，流行病学将得到培训。该计划维持57 在本科、博士前和博士后培训方面取得成功的教师培训师。因此，学生 不仅可以接触到在各种实验室动物物种上进行的研究项目（C。线虫，斑马鱼， 啮齿类动物、非人灵长类动物），而且还用于伴侣动物和食用动物的临床研究。越来越多的学生 表达了对跨学科的“同一健康”研究经验的兴趣，这些研究经验的假设针对复杂的 关于疾病在动物、人类及其 环境因此，我们动态地扩大了我们的培训教师，以满足学生的兴趣。的 我们短期培训计划的最大优势包括我们DVM的出色质量和动力 学生，我们的研究计划的强大的高度协作的多学科性质，和学生访问 使用创新方法的转化研究项目。学员将获得先进的 技术，如表观/基因组学和代谢组学，蛋白质组学，最先进的成像，BSL 3实验室， 转基因生物以及非生物和吸入设施。这次为期五年的竞争性续约 申请要求每年为总共15名DVM学生提供支持，为期五年（总共 75名学生），以维持T35计划的任务;激发下一代DVM的兴趣 临床科学家，将在学术界，政府和私营部门的领导地位。

Project Summary/Abstract. This is a competing renewal application of the highly successful UC Davis T35 STAR (Students Training in Advanced Research). The program has trained 225 DVM students over the last 20 years. Students are encouraged and mentored to submit hypothesis-driven research proposals during their first, second, and occasionally third year of the professional curriculum. The objective of the STAR program is to provide DVM students, whose application is approved by the review committee, stipend support to join experienced training faculty members and their productive research teams in 10 weeks of structured research mentoring and hands-on modern biomedical research. The program emphasizes 5 fundamental research objectives: 1) how to gain knowledge and understanding o f one’s field of science; 2 ) h o w t o formulate a scientifically sound and testable hypothesis; 3) identify specific objectives, conduct controlled methodical experiments, and develop technical expertise; 4) analyze results, derive conclusions, propose additional experiments, and anticipate new directions; and 5) convey research findings succinctly and convincingly to others. Responsible conduct of research and scientific rigor are key components of the training plan. STAR program has consistently received 55 to 63 applicants annually, and in 2015 expanded to 15 positions supported by the NIH T35 mechanism to meet growing demand from students with interest in participating in NIH-relevant research. Students with broad interests ranging from molecular and cellular medicine, to biomedical engineering, to vector borne diseases, to epidemiology will be trained. The program maintains 57 faculty trainers with proven successes in undergraduate, predoctoral and postdoctoral training. Thus, students have access to research projects conducted not only on a variety of lab animal species (C. elegans, zebrafish, rodents, non-human primate), but also clinical research on companion and food animals. Increasingly students express interest in transdisciplinary “One Health” research experiences with hypotheses targeting complex questions about disease emergence and transmission at the interface of animals, humans and their environment. Accordingly, we have dynamically expanded our training faculty to meet student interests. The greatest strengths of our short-term training program include the outstanding quality and motivation of our DVM students, the strong highly collaborative multidisciplinary nature of our research programs, and student access to translational research projects that use innovative approaches. Trainees will have access to advanced technologies, such as epi/genomics and metabolomics, proteomics, state-of-the-art imaging, BSL3 labs, genetically modified organisms, and gnotobiotic and inhalation facilities. This five-year competitive renewal application requests to maintain support for a total of 15 DVM students per year for each of five years (a total of 75 students), in order to maintain T35 program missions; spark the interest of the next generation of DVM clinician-scientists that will take leadership positions in academia, government, and the private sector.