Enhancing Drug Solubility Using Novel Dry Powder Coating Technology

缺乏不影响颗粒物理和化学性质的颗粒表面改性的可用技术。目前，70%的正在开发的新药表现出较差的溶解性，这为制药市场中的药物开发提供了巨大的挑战和高成本。目前的技术昂贵，产量低，不能处理不稳定的药物。阿斯顿粒子技术有限公司“APT”提供了一种新颖的一步粒子工程技术，在不使用溶剂和热量的情况下处理药物和材料。其USP在于以低成本为具有挑战性的药物（高剂量，湿敏或热敏）提供增强的颗粒特性。APTs溶解度增强项目旨在通过其颗粒分层技术增加难溶性药物的溶解度，包括那些不稳定的药物。

There is a lack of available technologies for particle surface modification that do not affect the particles physical and chemical properties. Currently 70% of new drugs being developed exhibit poor solubility and this provides a huge challenge and high cost for drug development in the pharmaceutical market. Current techniques are expensive, produce low yield and cannot process unstable drugs. Aston Particle Technologies Ltd. "APT" offers a novel one-step particle engineering technology that processes drugs and materials without the use of solvents and heat. Its USP lies in delivering enhanced particle properties for challenging drugs (high dose, moisture sensitive or heat sensitive) at low cost. APTs solubility enhancement project aims to increase the solubility of poorly soluble drugs, including those that are unstable, through its particle layering technology.