Synergy of novel chemistry & novel biology to combat unmet cleaning needs

生物启发的过程将对21世纪全球社会的挑战产生重大影响，包括与环境可持续性有关的挑战。在工业过程中使用生物催化剂有望促进从可再生资源中可持续地生产化学品、材料和燃料。这项提议的范围是鼓励学术研究及其成果通过探索绿色化学品和新生物技术的新合成途径，并将其成果转化为可持续生产经科学改进的生物材料的新的工业可用平台。绿色化学、分子生物学、酶技术和仪器分析技术将提供颠覆性的创新，并导致一种新的独特和可持续的产品的开发。在这一由可再生新化学品和新型洗涤剂生物分子组成的新产品的广泛潜在应用中，我们将成功地展示利用可再生原材料、化学合成、先进的蛋白质工程技术和稳健的生物制造技术来生产这些新生物材料的成本效益和工业兼容性，以及它在降低洗衣环境和经济成本方面的好处。通过将分析核磁共振应用于新型生物材料-化学和生物分子，可以验证它们的结构一致性，并研究它们对衣服上的皮脂污染，作为一种极好的技术工具，有可能加速设计和创造使用新洗涤剂的与冷洗相关的新型HPC产品配方。

"Bio-inspired processes will have a major impact on the challenges of the global society in the 21st century, including those associated with environmental sustainability. The employment of biocatalysts in industrial processes is expected to boost a sustainable production of chemicals, materials and fuels from renewable resources.The scope of this proposal is to encourage and translate academic research and its outcome into a novel industrially usable platform for the sustainable production of scientifically improved biomaterials by exploiting new synthesis pathways for green chemicals and novel biotechnological technologies. Green chemistry, molecular biology, enzyme technology and instrumental analytics will provide disruptive innovation and lead to the development of a novel unique and sustainable product.Amongst the broad spectrum of potential applications for this novel product comprising renewable novel chemicals and a novel detergent biomolecule, we will successfully demonstrate the cost-efficient and industrially compatible production of these new biomaterials using renewable raw materials, chemical synthesis, advanced protein engineering technologies and robust bio-manufacturing technology and its benefits in reducing the environmental and economic costs of laundry.By applying analytical NMR to the novel biomaterials -- chemical and biomolecular, their structural conformity can be verified and sebum contaminations on clothes studied, serving as an excellent technical tool to potentially accelerate design and creation of cold-cleaning relevant novel HPC product formulations with new detergents."