New smart diagnostics for infection

目前，诊断细菌感染和选择正确的抗生素治疗可能需要长达48小时，这通常导致临床医生开出广谱抗生素，这可能导致抗生素耐药性的发展。该项目旨在开发在中国使用的快速、准确和经济的诊断测试，在不需要复杂的实验室设备的情况下，在30分钟内提供诊断。此外，这些检测将提供关于抗生素耐药性的重要信息，从而使临床医生能够开出最有效的治疗方案，避免产生抗生素耐药性。该项目还旨在开发一种治疗药物监测（TDM）系统，通过简单的血液测试可以准确监测抗生素治疗。TDM将确保患者接受针对特定感染的正确剂量的抗生素，从而确保感染的快速治疗并避免抗生素耐药性。该项目还将开发一个以知识为基础的平台，帮助医生跟踪中国的传染病，并就适当的控制策略向医生提供建议。

Currently, diagnosing a bacterial infection and selecting the correct antibiotic treatment can take up to 48hrsand this often results in clinicians prescribing broad spectrum antibiotics, which may result in the developmentof antibiotic resistance. This project aims to develop rapid, accurate and economical diagnostic tests for use inChina that will provide a diagnosis in less than 30 minutes without the need for complex laboratory equipment.Furthermore, the tests will provide important information on antibiotic resistance, therefore enabling theclinician to prescribe the most effective treatment and avoid the development of antibiotic resistance.The project also aims to develop a Therapeutic Drug Monitoring (TDM) system that antibiotic treatments canbe accurately monitored through a simple blood test. The TDM will ensure that patients receive the correctdosages of antibiotics for a given infection, thus ensuring rapid treatment of the infection and avoidance ofantibiotic resistance. The project will also develop a knowledge-based platform will help physicians trackinfectious disease in China and provide advice to physicians on appropriate control strategies.