GROWTH AND HEALTH STUDY

NHLBI增长与健康研究扩展(NGHS III)将继续 由2379名黑人和白人女孩组成的队列在1987年首次测量 分别是9岁和10岁.主要的研究目标仍然是 肥胖症差异发展的前因研究 在黑人和白人青春期女性中的程度的测定 肥胖发展过程中的差异与此相关 其他冠状动脉血管疾病危险因素的差异，如血液 血压、血脂/脂蛋白和载脂蛋白。 这项研究跟踪了这些女孩在厄尔和青春期中期的情况；五岁 建议延长一年，以继续进行考试，直至 青春期后期，成年女性的成熟模式形成的时期。 注意饮食习惯、体力活动 模式、社会经济地位、心理社会和文化因素，早期 怀孕，以及生活方式的改变和选择。该研究将评估：(1) 反映肥胖和体脂分布的人体测量参数， (2)饮食摄入量和体力活动的变化；(3)心理社会变化 测量自尊、压力、健康观念、抑郁和 绝望，(4)血压、血脂、血糖和胰岛素，以及 (5)人口因素。 伯克利临床中心目前看到了大约85%的 原始参与者，建议通过以下方式提高其队列遵从率 去看望那些搬到研究区以外的阿瑞斯的女孩。 就像在PST一样，当地女孩将继续出现在她们的家中 或者是在当地的医院现场。现有的详细研究方案和 正在接受培训并获得认证的验尸官和 面谈人员将确保高质量的数据收集。这项研究将 继续提供重要的科学信息以帮助澄清病因 黑人青少年中肥胖和高血压的高发病率 女孩，跟踪与心血管疾病相关的风险因素的发展 黑人女性的死亡率，并确定这些因素之间的相互关系 这些因素，最终促进了对妇女健康的有效干预。

The NHLBI Growth & Health Study Exension (NGHS III) will continue to follow a cohort of 2,379 black and white girls first measured in 1987 when they were 9 nd 10 years old. The primary research goals continue to be the investigation of the antecedent of the differential development of obesity in black and white adolescent females and the determination of the degree to which differences in the development of obesity are associated with differences in other coronary vascular disease risk factors, such as blood pressure, blood lipids/lipoproteins and apolipoproteins. The study has tracked the girls through earl and mid-adolescence; a five year extension is proposed to continue examinations through that stage of late adolescence when patterns of adult womanhood become established. Attention will be directed toward dietary habits, physical activity patterns, socioeconomic status, psychosocial and cultural factors, early pregnancy, and lifestyle changes and choices. The Study will assess: (1) anthropometric parameters reflecting obesity and distribution of body fat, (2) changes in dietary intake and physical activity, (3) psychosocial measures of self-esteem, stress, health perceptions, depression and hopelessness, (4) blood pressure, blood lipids, glucose and insulin, and (5) demographic factors. The Berkeley clinical center, currently seeing approximately 85% of its original enrollees, proposes to increase its rate of cohort compliance by traveling to see those girls who have moved to ares outside the study area. As in the pst, local girls will continue to be seen either at their homes or at a local hospital site. The existent detailed research protocol and the ongoing trained and certified staff of medical examiners and interviewers will ensure high quality data collection. The Study will continue to yield important scientific information to help clarify etiology of the higher incidence of obesity and hypertension in black adolescent girls, track the development of the risk factors associated with CVD mortality in black women, and identify the interrelationship of these factors, ultimately promoting effective interventions in women's health.