GROWTH AND HEALTH STUDY

国家心肺和血液辛辛那提临床中心 研究所的生长与健康研究，连同其合作 中心，建议扩展到目前的研究，使NGHS队列 从9岁和10岁到15岁， 16年可以从青春期后期到成年早期 以描述CVD危险因素的差异。 的目标 NGHS倡议是描述和解释a）发生率较高的 青春期黑人女性肥胖和B）其与主要 心血管疾病（CVD）危险因素。 辛辛那提中心， 因此，建议在女孩队列中再测量四年： 1)前因因素（如饮食、运动和心理社会因素）/ 2） 体型（如身高、体重、皮褶和周长，以及 成熟状态）;和30个受体型影响的CVD风险因素（例如， 血压和血脂）。 辛辛那提中心举办了一个学校- 基于NGHS的研究：受试者从四年级和五年级入组 辛辛那提及周边地区公立和教区学校的班级 汉密尔顿县从种族，地理和 该地区的社会经济代表。 辛辛那提中心 招收了870名学生，432名白色学生和438名黑人学生。 在NGHS结束时， 女孩年龄为15和16岁。 在扩展研究（NGHS-III）中，受试者 年龄在16-20岁之间。 辛辛那提中心将继续一所学校- 基础的学习，只要s科目可以在学校看到。 有些科目将 由于各种原因（例如， 移动到该地区以外，但在辛辛那提100英里内，转移 学校将不合作的研究（这还没有发生） （或辍学）。

The Cincinnati Clinical Center of the National Heart Lung and Blood Institute's Growth and Health Study, in conjunction with its collaborating centers, proposes an extension to the current study so that the NGHS cohort which has been followed for seven years from ages 9 and 10 years to ages 15 and 16 years can be followed through late adolescence into early adulthood in order to describe the divergence of CVD risk factors. The goals of the NGHS initiative were to describe and explain a) the greater incidence of obesity in black females during adolescence and b) its association to major cardiovascular disease (CVD) risk factor. The Cincinnati Center, therefore, proposes to measure in the cohort of girls for four more years: 1) antecedent factors (e.g. diet, exercise, and psychosocial factors)/ 2) body habitus (e.g. height, weight, skinfolds, and circumferences, and maturation status); and 30 CVD risk factors affected by body habitus (e.g. blood pressure and lipids). The Cincinnati Center has conducted a school- based study in NGHS:subjects were enrolled from the fourth and fifth grade classes of public and parochial schools in Cincinnati and surrounding Hamilton County selected from to be racially, geographically, and socioeconomically representative of the area. The Cincinnati Center enrolled 870 students, 432 white and 438 black. At the end of NGHS, the girls will be ages 15 and 16 years. In the extension (NGHS-III), subjects will be ages 16-20 years. The Cincinnati Center will continue a school- based study, as long s subjects can be seen at school. Some subjects will be seen at Children's Hospital or their home for a variety of reasons (e.g. moving outside the area, but within 100 miles of Cincinnati, transferring to a school which will not cooperate with the study (this has not occurred to-date), or dropping out of school.)